Living liver donor: indications and technical aspects

Living donor liver transplantation (LDLT) nowadays represents an important and safe alternative to conventional deceased donor liver transplantation (DDLT). A major concern related to the LDLT procedure is still represented by donor safety because a serious operation not without risks must be carrie...

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Bibliographic Details
Published in:Chirurg 2015-06, Vol.86 (6), p.609-21; quiz 622
Main Authors: Nadalin, S, Capobianco, I, Königsrainer, I, Harder, B, Königsrainer, A
Format: Article
Language:ger
Subjects:
Donor Selection
Germany
Hepatectomy - methods
Humans
Liver Transplantation - methods
Living Donors
Patient Safety
Postoperative Complications - etiology
Postoperative Complications - mortality
Survival Rate
Tissue and Organ Harvesting - methods
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Summary:Living donor liver transplantation (LDLT) nowadays represents an important and safe alternative to conventional deceased donor liver transplantation (DDLT). A major concern related to the LDLT procedure is still represented by donor safety because a serious operation not without risks must be carried out on a healthy individual. In the present review of the indications for LDLT the technical concepts of donor surgery, criteria for donor selection and evaluation and morbidity and mortality results related to the procedure are presented. In general, the indications for LDLT are almost the same as for DDLT. The donor hepatectomy (right, left or left lateral) is presented in five main phases. The reported morbidity rates vary between 10 % and 60 % and are strongly related to the experience of the transplant center. The currently reported postoperative mortality rates for left and right hepatectomy are 0.1 % and 0.5 %, respectively. The results of LDLT are similar if not even better than those for DDLT depending on the specific indications.
ISSN:1433-0385
DOI:10.1007/s00104-015-0017-9