Plasma CTRP-3 concentrations in Chinese patients with obesity and type II diabetes negatively correlate with insulin resistance

Background To analyze the association between the plasma C1q/TNF-related protein-3 (CTRP-3) concentrations, obesity, and type II diabetes in the Chinese population. Methods The plasma CTRP-3 concentrations were analyzed in 174 Chinese subjects with obesity (n = 43), type II diabetes (n = 41), obesit...

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Bibliographic Details
Published in:Journal of clinical lipidology 2015-05, Vol.9 (3), p.289-294
Main Authors: Qu, Hua, PhD, Deng, Min, MD, Wang, Hang, MD, Wei, Huili, PhD, Liu, Fang, MD, Wu, Jing, MD, Deng, Huacong, PhD
Format: Article
Language:English
Subjects:
Aged
Asian Continental Ancestry Group
Blood Glucose - metabolism
Cardiovascular
China
CTRP-3
Diabetes Mellitus, Type 2 - blood
Female
Humans
Inflammation
Inflammation - blood
Insulin Resistance
Lipid Metabolism
Male
Middle Aged
Obesity
Obesity - blood
Tumor Necrosis Factors - blood
Type II diabetes mellitus
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Summary:Background To analyze the association between the plasma C1q/TNF-related protein-3 (CTRP-3) concentrations, obesity, and type II diabetes in the Chinese population. Methods The plasma CTRP-3 concentrations were analyzed in 174 Chinese subjects with obesity (n = 43), type II diabetes (n = 41), obesity combined with type II diabetes (n = 45), and healthy subjects (n = 45), as were various clinical parameters of obesity-related metabolic disorders and adipokines. Results The plasma CTRP-3 concentrations were significantly lower in patients with obesity and type II diabetes than in healthy subjects ( P  
ISSN:1933-2874
1876-4789
DOI:10.1016/j.jacl.2015.03.006