Clonal diversity in glioblastoma: is it clinically relevant?

"Serial tumor sampling, single-cell genomics and quantitative imaging are all available technologies, but their integration into current pathways of care will require a paradigm shift in the clinical management of patients with glioblastoma."

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Bibliographic Details
Published in:Future oncology (London, England) England), 2015-06, Vol.11 (12), p.1703-1706
Main Authors: Watts, Colin, Piccirillo, Sara GM
Format: Article
Language:English
Subjects:
brain
Brain Neoplasms - genetics
Brain Neoplasms - pathology
Brain Neoplasms - therapy
cancer
cancer stem cells
clinical trials
Disease Progression
evolution
genomics
glioblastoma
Glioblastoma - genetics
Glioblastoma - pathology
Glioblastoma - therapy
Humans
Molecular Targeted Therapy
Mutation
sampling bias
Signal Transduction
therapy
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Description
Summary:"Serial tumor sampling, single-cell genomics and quantitative imaging are all available technologies, but their integration into current pathways of care will require a paradigm shift in the clinical management of patients with glioblastoma."
ISSN:1479-6694
1744-8301
DOI:10.2217/fon.15.73