Uterine artery embolization for uterine arteriovenous malformation in five women desiring fertility: pregnancy outcomes

Uterine arteriovenous malformations (AVM) are rare and can be classified as either congenital or acquired. Acquired AVMs may result from trauma, uterine instrumentation, infection or gestational trophoblastic disease. The majority of acquired AVMs are encountered in women of reproductive age with a...

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Bibliographic Details
Published in:Human reproduction (Oxford) 2015-07, Vol.30 (7), p.1599-1605
Main Authors: Vilos, Angelos G., Vilos, George A., Hollett-Caines, Jackie, Rajakumar, Chandrew, Garvin, Greg, Kozak, Roman
Format: Article
Language:English
Subjects:
Adolescent
Adult
Arteriovenous Malformations - surgery
Female
Fertility Preservation
Humans
Pregnancy
Pregnancy Outcome
Uterine Artery - abnormalities
Uterine Artery Embolization - methods
Young Adult
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Summary:Uterine arteriovenous malformations (AVM) are rare and can be classified as either congenital or acquired. Acquired AVMs may result from trauma, uterine instrumentation, infection or gestational trophoblastic disease. The majority of acquired AVMs are encountered in women of reproductive age with a history of at least one pregnancy. Traditional therapies of AVMs include medical management of symptomatic bleeding, blood transfusions, uterine artery embolization (UAE) or hysterectomy. In this retrospective case series, we report our experience with AVM and UAE in five symptomatic women of reproductive age who wished to preserve fertility. Patients were 18–32 years old, and had 1–3 previous pregnancies prior to initial presentation. All patients were followed until their deliveries. All five patients delivered live births. Three of the five patients required two embolization procedures and one of these women required a subsequent hysterectomy. Two deliveries were at term and had normal weight babies and normal placenta. One woman had cerclage placed and developed chorioamnionitis at 34 weeks but had a normal placenta. Two pregnancies were induced
ISSN:0268-1161
1460-2350
DOI:10.1093/humrep/dev097