Statin Prescribing Patterns: An Analysis of Data From Patients With Diabetes in the National Hospital Ambulatory Medical Care Survey Outpatient Department and National Ambulatory Medical Care Survey Databases, 2005–2010

• Published in: Clinical therapeutics 2015-06, Vol.37 (6), p.1329-1339
• Main Authors: Pauff, Brandy R., BS, Jiroutek, Michael R., DrPH, MS, Holland, Melissa A., PharmD, MSCR, Sutton, Beth S., PhD
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age; Age Factors; Aged; Body Mass Index; Cardiovascular disease; Cardiovascular Diseases - prevention & control; Cholesterol; Cross-Sectional Studies; Diabetes; Diabetes Mellitus - drug therapy; disparities; Drug Prescriptions - statistics & numerical data; Ethnicity; Female; Field representatives; Health Care Surveys; Hispanic Americans; Hispanic Americans - statistics & numerical data; Hospitals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Hyperlipidemias - drug therapy; Hypertension; Hypertension - drug therapy; Internal Medicine; Lipids; Male; Medical Education; Middle Aged; Multivariate analysis; Patients; Practice Patterns, Physicians; Primary care; Retrospective Studies; Risk factors; statins; Studies; United States; Young Adult
• ISSN: 0149-2918; 1879-114X
• DOI: 10.1016/j.clinthera.2015.03.020

Abstract Purpose In 2008, the American Diabetes Association (ADA) recommended that patients aged >40 years with diabetes and cardiovascular disease or with ≥1 cardiovascular disease risk factor be prescribed a statin. This study assessed statin prescribing patterns in patients with diabetes, per the ADA guideline, using data from the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey–Outpatient Department for the years 2005 to 2010. This study also examined patients’ demographic characteristics associated with statin prescribing, including sex, age, ethnicity, race, insurance type, body mass index, region, primary care provider, hypertension and hyperlipidemia. Methods This retrospective, cross-sectional, observational study included data dated between 2005 and 2010 from patients aged ≥18 years with diabetes and without contraindications to statin use. Associations between statin prescribing and variables of interest were analyzed using χ2 tests. A multivariate logistic regression model included 2 groups stratified by 3-year observation period (2005–2007 and 2008–2010) plus all variables with an overall χ2 test result of P < 0.2. P values, odds ratios (ORs) and 95% CIs are reported. Findings The majority of patients were aged ≥40 years (93.1%), had a body mass index of ≥30 (58.7%), had hypertension (65.6%), and did not have hyperlipidemia (54.0%). A low percentage of patients were prescribed a statin (35.1%), but it appears that this percentage is on the rise. During 2005–2007, 31.9% of patients received a statin, whereas 37.7% of patients received a statin during 2008–2010. After adjustment for covariates included in the multivariate logistic regression model, those with hypertension (vs none [reference]: OR = 1.31; 95% CI, 1.12–1.53) and/or hyperlipidemia (vs none [reference]: OR = 4.44; 95% CI, 3.70–5.33) were significantly more likely to have been prescribed a statin, whereas those in age group 18–