Does Mood Disorder Questionnaire identify sub-threshold bipolarity? Evidence studying worsening of quality of life

Abstract Objective It is debated whether the Mood Disorder Questionnaire (MDQ) can generate false positives by screening other disorders as bipolar, or identify sub-threshold bipolarity. The aim is to verify if Quality of Life (QoL) impairment in MQD positives in the community is due to MDQ positivi...

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Bibliographic Details
Published in:Journal of affective disorders 2015-09, Vol.183, p.173-178
Main Authors: Carta, Mauro Giovanni, Norcini-Pala, Andrea, Moro, Maria Francesca, Balestrieri, Matteo, Caraci, Filippo, Dell’Osso, Liliana, Sciascio, Guido Di, Faravelli, Carlo, Hardoy, Maria Carolina, Aguglia, Eugenio, Roncone, Rita, Nardi, Antonio Egidio, Drago, Filippo
Format: Article
Language:English
Subjects:
Adult
Affect
Aged
Bipolar Disorder - diagnosis
Bipolar Disorder - psychology
Bipolar disorders
Early Diagnosis
False Positive Reactions
Female
Humans
Italy
Male
Mass Screening - methods
Middle Aged
Mood Disorder Questionnaire
Mood Disorders - complications
Psychiatry
Quality of life
Quality of Life - psychology
Screening
Spectrum
Surveys and Questionnaires - standards
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Summary:Abstract Objective It is debated whether the Mood Disorder Questionnaire (MDQ) can generate false positives by screening other disorders as bipolar, or identify sub-threshold bipolarity. The aim is to verify if Quality of Life (QoL) impairment in MQD positives in the community is due to MDQ positivity itself, or to psychiatric diagnosis associated with MDQ positivity (supporting the former hypothesis). Method Community survey. Sample randomized after stratification of the adult population in the records of seven Italian regions. Tools: MDQ; Short Form Health Survey (SF-12); semi-structured clinical interview carried out by clinicians. Results Positives at MDQ show worsening QoL with an attributable burden of 2.8±1.8 lower than in MDD (5.6±3.6, p
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2015.04.058