Comparison of Outcomes and Presentation in Men-Versus-Women With Bicuspid Aortic Valves Undergoing Aortic Valve Replacement

• Published in: The American journal of cardiology 2015-07, Vol.116 (2), p.250-255
• Main Authors: Andrei, Adin-Cristian, PhD, Yadlapati, Ajay, MD, Malaisrie, S. Chris, MD, Puthumana, Jyothy J., MD, Li, Zhi, MS, Rigolin, Vera H., MD, Mendelson, Marla, MD, Clennon, Colleen, BSN, Kruse, Jane, BSN, Fedak, Paul W.M., MD, Thomas, James D., MD, Higgins, Jennifer A., MD, Rinewalt, Daniel, MD, Bonow, Robert O., MD, McCarthy, Patrick M., MD
• Format: Article
• Language: English
• Subjects: Aortic Valve - abnormalities; Aortic Valve - diagnostic imaging; Aortic Valve - surgery; Bicuspid Aortic Valve Disease; Cardiology; Cardiovascular; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Heart Valve Diseases - diagnostic imaging; Heart Valve Diseases - mortality; Heart Valve Diseases - surgery; Heart Valve Prosthesis; Hospital Mortality - trends; Humans; Male; Middle Aged; Mortality; Postoperative Complications - mortality; Retrospective Studies; Risk Factors; Survival Rate - trends; Treatment Outcome; United States - epidemiology
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2015.04.017

Gender disparities in short- and long-term outcomes have been documented in cardiac and valvular heart surgery. However, there is a paucity of data regarding these differences in the bicuspid aortic valve (BAV) population. The aim of this study was to examine gender-specific differences in short- and long-term outcomes after surgical aortic valve (AV) replacement in patients with BAV. A retrospective analysis was performed in 628 consecutive patients with BAV who underwent AV surgery from April 2004 to December 2013. To reduce bias when comparing outcomes by gender, propensity score matching obtained on the basis of potential confounders was used. Women with BAV who underwent AV surgery presented with more advanced age (mean 60.7 ± 13.8 vs 56.3 ± 13.6 years, p