One-Pot Synthesis of Pyrrolo­[1,2‑a]­quinoxaline Derivatives via a Copper-Catalyzed Aerobic Oxidative Domino Reaction

A copper-catalyzed process for the synthesis of pyrrolo­[1,2-a]­quinoxalines from readily available α-amino acids and 1-(2-halophenyl)-1H-pyrroles is described. Different functional groups were well tolerated to give the corresponding products.

Saved in:
Bibliographic Details
Published in:Organic letters 2015-06, Vol.17 (12), p.2932-2935
Main Authors: Liu, Huanhuan, Duan, Tiantian, Zhang, Zeyuan, Xie, Caixia, Ma, Chen
Format: Article
Language:English
Subjects:
Catalysis
Copper - chemistry
Molecular Structure
Organometallic Compounds - chemistry
Oxidation-Reduction
Pyrroles - chemical synthesis
Pyrroles - chemistry
Quinoxalines - chemical synthesis
Quinoxalines - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A copper-catalyzed process for the synthesis of pyrrolo­[1,2-a]­quinoxalines from readily available α-amino acids and 1-(2-halophenyl)-1H-pyrroles is described. Different functional groups were well tolerated to give the corresponding products.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.5b01167