Rotational correlation time in irradiated DNA

The flexibility of high molecular weight DNA, extracted from mammalian cells and exposed to various doses of gamma -rays, was studied with the technique of perturbed angular correlations. The irradiation was monitored to three different doses, i.e., 20, 40 and 80 Gy, using a cobalt-60 source. The re...

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Bibliographic Details
Published in:Journal of non-crystalline solids 1994-01, Vol.172-7 (pt 2), p.1121-1124
Main Authors: Kalfas, CA, Sideris, E G, Loukakis, G K, Anagnostopoulou-Konsta, A
Format: Article
Language:English
Online Access:Get full text
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Summary:The flexibility of high molecular weight DNA, extracted from mammalian cells and exposed to various doses of gamma -rays, was studied with the technique of perturbed angular correlations. The irradiation was monitored to three different doses, i.e., 20, 40 and 80 Gy, using a cobalt-60 source. The results indicate that the flexibility of the irradiated samples is lower than that of the control (non-radiated) sample, supporting the notion of `segmental flexibility'.
ISSN:0022-3093