Exclusive enteral nutrition continues to be first line therapy for pediatric Crohn's disease in the era of biologics

Exclusive enteral nutrition (EEN) has been to be more effective than corticosteroids in achieving mucosal healing without their side effects. To determine the efficacy of EEN in terms of inducing clinical remission in newly diagnosed CD children and to study the efficacy of this therapeutic approach...

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Bibliographic Details
Published in:Anales de pediatría (Barcelona, Spain : 2003) Spain : 2003), 2015-07, Vol.83 (1), p.47-54
Main Authors: Navas-López, V M, Blasco-Alonso, J, Lacasa Maseri, S, Girón Fernández-Crehuet, F, Serrano Nieto, M J, Vicioso Recio, M I, Sierra Salinas, C
Format: Article
Language:Spanish
Subjects:
Biological Products - therapeutic use
Child
Crohn Disease - therapy
Enteral Nutrition
Female
Humans
Male
Remission Induction
Retrospective Studies
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Summary:Exclusive enteral nutrition (EEN) has been to be more effective than corticosteroids in achieving mucosal healing without their side effects. To determine the efficacy of EEN in terms of inducing clinical remission in newly diagnosed CD children and to study the efficacy of this therapeutic approach in improving the degree of intestinal mucosa inflammation. The medical records of patients with newly diagnosed Crohn's disease treated with EEN were reviewed retrospectively. The degree of mucosal inflammation was assessed by fecal calprotectin (FC). Remission was defined as a PCDAI
ISSN:1695-9531
DOI:10.1016/j.anpedi.2014.02.027