Derivation of gender and age-specific reference intervals from fully normal Japanese individuals and the implications for health screening

With nationwide standardization of laboratory tests among institutions for health screening in Japan, common reference intervals (RIs) were derived from records of 1,500,000 health check attendees. Targets were 20 basic laboratory tests including body mass index (BMI) and systolic and diastolic bloo...

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Bibliographic Details
Published in:Clinica chimica acta 2015-07, Vol.447, p.105-114
Main Authors: Yamakado, Minoru, Ichihara, Kiyoshi, Matsumoto, Yoshiyuki, Ishikawa, Yoshiki, Kato, Kiminori, Komatsubara, Yusuke, Takaya, Norihide, Tomita, Shohken, Kawano, Reo, Takada, Keisuke, Watanabe, Kiyoaki
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Clinical decision limit
Clinical Decision-Making
Clinical guideline
Female
Health - standards
Health screening
Humans
Japan
Male
Mass Screening - standards
Middle Aged
Reference individual
Reference interval
Reference Values
Sex Factors
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Summary:With nationwide standardization of laboratory tests among institutions for health screening in Japan, common reference intervals (RIs) were derived from records of 1,500,000 health check attendees. Targets were 20 basic laboratory tests including body mass index (BMI) and systolic and diastolic blood pressures (SBP, DBP). Individuals fulfilling the following strict criteria were chosen: SBP
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2015.04.037