Nail psoriasis as a predictor of the development of psoriatic arthritis

Abstract Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30% of patients with psoriasis. Various imaging studies have demonstrated that there is a considerable proportion of undiagnosed psoriatic arthritis among patients with psoriasis. Since early detection and trea...

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Bibliographic Details
Published in:Actas dermo-sifiliográficas 2015-07, Vol.106 (6), p.452-457
Main Authors: Raposo, I, Torres, T
Format: Article
Language:English
Subjects:
Arthritis, Psoriatic - classification
Arthritis, Psoriatic - diagnosis
Arthritis, Psoriatic - etiology
Arthritis, Psoriatic - pathology
Artritis psoriásica
Comorbidity
Dermatology
Diagnostic Errors
Disease Progression
Early Diagnosis
Entesitis
Entesopatía
Enthesitis
Enthesopathy
Enthesopathy - complications
Enthesopathy - physiopathology
Finger Joint - diagnostic imaging
Finger Joint - pathology
HLA-C Antigens - immunology
Humans
Inflammation
Magnetic Resonance Imaging
Nail
Nail Diseases - pathology
Nail Diseases - physiopathology
Onychomycosis - diagnosis
Psoriasis
Psoriasis - pathology
Psoriasis - physiopathology
Psoriatic arthritis
Uña
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Summary:Abstract Psoriatic arthritis is a psoriasis-related spondyloarthropathy that occurs in 20–30% of patients with psoriasis. Various imaging studies have demonstrated that there is a considerable proportion of undiagnosed psoriatic arthritis among patients with psoriasis. Since early detection and treatment of psoriatic arthritis could, ultimately, allow the prevention of clinical and radiologic progression of the disease, there is the need to establish clinical indicators to detect this risk. Nail psoriasis has been proposed as a predictor for the development of psoriatic arthritis. The inflammation involving the entheses, called enthesitis, is an early inflammatory change seen in psoriatic arthritis, and nail changes appear to result from the close relationship between the nail and the enthesis of the distal interphalangeal extensor tendon, one of the main entheseal compartments affected in psoriatic arthritis. As skin lesions precede articular symptoms in more than 75–80% of patients with psoriatic arthritis, dermatologists may play a key role in the early detection and management of psoriatic arthritis.
ISSN:0001-7310
2173-5778
1578-2190
DOI:10.1016/j.ad.2015.02.005