Antimicrobial resistance in Helicobacter pylori: current situation and management strategy in Vietnam

• Published in: Journal of infection in developing countries 2015-07, Vol.9 (6), p.609-613
• Main Authors: Phan, Trung Nam, Tran, Van Huy, Tran, Thi Nhu Hoa, Le, Van An, Santona, Antonella, Rubino, Salvatore, Paglietti, Bianca
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Antimicrobial agents; Drug resistance; Drug Resistance, Bacterial; Drug Therapy, Combination - methods; Helicobacter Infections - drug therapy; Helicobacter Infections - epidemiology; Helicobacter Infections - microbiology; Helicobacter pylori - drug effects; Helicobacter pylori - isolation & purification; Humans; Microbial Sensitivity Tests; Vietnam - epidemiology
• ISSN: 1972-2680; 2036-6590; 1972-2680
• DOI: 10.3855/jidc.6942

Increasing antimicrobial resistance to key antibiotics in Helicobacter pylori has become a main cause of treatment failures in many countries, including Vietnam. For this reason it is advisable to perform antimicrobial sensitivity tests to provide more focused regimens for H. pylori eradication. However, this approach is generally unavailable for H. pylori in Vietnam and the selection of treatment regimens is mainly based on the trend of antibiotic use in the population, resistance development in the region, and history of H. pylori eradication of patients. The aim of this review is to examine the current situation of antimicrobial resistance in Vietnam and suggest management strategies for treatment selection.