SYNTHESIS OF SCHIFF BASES FROM NATURAL PRODUCTS AND THEIR REMARKABLE ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY

Schiff bases have been synthesized by the condensation of primary amine with aldehyde under organic solvent free condition. Many methods of Schiff base synthesis are reported but the objective is that to utilize such method and reagents which is environment friendly along with good yield. Most organ...

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Bibliographic Details
Published in:FUUAST jounral of biology 2014-06, Vol.4 (1), p.27-27
Main Authors: Wahab, Aneela, Haider, Syed Sajjad, Mahmood, Iffat, Mahmood, Talat, Sherwani, Sikandar Khan, Kanwal, Sandaleen
Format: Article
Language:English
Subjects:
Tamarindus indica
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Summary:Schiff bases have been synthesized by the condensation of primary amine with aldehyde under organic solvent free condition. Many methods of Schiff base synthesis are reported but the objective is that to utilize such method and reagents which is environment friendly along with good yield. Most organic reactions utilized organic solvents and acids in which some are curse for environment because of this reason the authors did not use any organic solvent and acid. In this method Benzaldehyde is reacted with Aniline and Urea in the presence of natural acid extracted from tamarind and lemon to give Schiff bases SP-5 and SP-18. The products (SP-5 and SP-18) were identified by various spectroscopic techniques such as IR, Mass and ^sup 1^H-NMR. The synthesis of SP-5 from tamarind and SP-18 from lemon is a new environmental friendly method for the synthesis of Schiff base. The present work revealed that Schiff bases with potential biological activity can easily be synthesized in the presence of natural acids as a catalyst.
ISSN:2222-0356
2616-8758