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History of Mechanical Ventilation. From Vesalius to Ventilator-induced Lung Injury

Mechanical ventilation is a life-saving therapy that catalyzed the development of modern intensive care units. The origins of modern mechanical ventilation can be traced back about five centuries to the seminal work of Andreas Vesalius. This article is a short history of mechanical ventilation, trac...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2015-05, Vol.191 (10), p.1106-1115
Main Author: Slutsky, Arthur S
Format: Article
Language:English
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Summary:Mechanical ventilation is a life-saving therapy that catalyzed the development of modern intensive care units. The origins of modern mechanical ventilation can be traced back about five centuries to the seminal work of Andreas Vesalius. This article is a short history of mechanical ventilation, tracing its origins over the centuries to the present day. One of the great advances in ventilatory support over the past few decades has been the development of lung-protective ventilatory strategies, based on our understanding of the iatrogenic consequences of mechanical ventilation such as ventilator-induced lung injury. These strategies have markedly improved clinical outcomes in patients with respiratory failure.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201503-0421pp