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Older adults recently started on psychotropic medication: where are the symptoms?

Objective The objective of this study is to understand the characteristics of older adults on newly prescribed psychotropic medication with minimal psychiatric symptoms. Methods Naturalistic cohort study of non‐institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assist...

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Published in:International journal of geriatric psychiatry 2015-06, Vol.30 (6), p.580-586
Main Authors: Maust, Donovan T., Chen, Shirley H., Benson, Amy, Mavandadi, Shahrzad, Streim, Joel E., DiFilippo, Suzanne, Snedden, Thomas M., Oslin, David W.
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container_title International journal of geriatric psychiatry
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creator Maust, Donovan T.
Chen, Shirley H.
Benson, Amy
Mavandadi, Shahrzad
Streim, Joel E.
DiFilippo, Suzanne
Snedden, Thomas M.
Oslin, David W.
description Objective The objective of this study is to understand the characteristics of older adults on newly prescribed psychotropic medication with minimal psychiatric symptoms. Methods Naturalistic cohort study of non‐institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assistance Contract for the Elderly. Persons newly prescribed antidepressant or anxiolytic monotherapy or combination therapy were contacted for clinical assessment by a telephone‐based behavioral health service. The initial assessment included standardized mental health screening instruments and scales including the Blessed Orientation‐Memory‐Concentration test, Patient Health Questionnaire‐9, Generalized Anxiety Disorder‐7, and Medical Outcomes Survey (SF‐12). In addition, patients were asked for their understanding of the prescription indication. Results Of the 254 participants who met minimal symptom criteria (Patient Health Questionnaire‐9 
doi_str_mv 10.1002/gps.4187
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Methods Naturalistic cohort study of non‐institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assistance Contract for the Elderly. Persons newly prescribed antidepressant or anxiolytic monotherapy or combination therapy were contacted for clinical assessment by a telephone‐based behavioral health service. The initial assessment included standardized mental health screening instruments and scales including the Blessed Orientation‐Memory‐Concentration test, Patient Health Questionnaire‐9, Generalized Anxiety Disorder‐7, and Medical Outcomes Survey (SF‐12). In addition, patients were asked for their understanding of the prescription indication. Results Of the 254 participants who met minimal symptom criteria (Patient Health Questionnaire‐9 &lt; 5 and Generalized Anxiety Disorder‐7 &lt; 5), women comprised slightly more of the anxiolytic compared with antidepressant monotherapy group (88.9% vs. 76.7%, p = 0.04). The most common self‐reported reason for prescription of an antidepressant or anxiolytic was depression or anxiety, respectively, despite near‐absence of these symptoms on clinical assessment. Comparing monotherapy to combination therapy groups, those with combination therapy were more likely to report a history of depression (12.6% vs. 1.8%, p &lt; 0.001) and also report depression as the reason for the prescription (40.2% vs. 21.0%, p &lt; 0.01). Conclusions In this sample of older adults on new psychotropic medication with minimal psychiatric symptoms, there are few patient characteristics that distinguish those on antidepressant versus anxiolytic monotherapy or those on monotherapy versus combination therapy. While quality of care in late‐life mental health has focused on improving detection and treatment, there should be further attention to low‐symptom patients potentially receiving inappropriate pharmacotherapy. Copyright © 2014 John Wiley &amp; Sons, Ltd.</description><identifier>ISSN: 0885-6230</identifier><identifier>EISSN: 1099-1166</identifier><identifier>DOI: 10.1002/gps.4187</identifier><identifier>PMID: 25116369</identifier><identifier>CODEN: IJGPES</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Aged ; Aged, 80 and over ; Anti-Anxiety Agents - therapeutic use ; Antidepressive Agents - therapeutic use ; Anxiety Disorders - drug therapy ; Cohort Studies ; Community health care ; Depressive Disorder - drug therapy ; Drug therapy ; Female ; Geriatric psychiatry ; Geriatric psychology ; Health Knowledge, Attitudes, Practice ; Health Status ; Humans ; Male ; Mental Disorders - diagnosis ; Mental Disorders - drug therapy ; Mental health care ; Middle Aged ; older adults ; Older people ; Pennsylvania ; primary care ; Psychiatric Status Rating Scales ; Psychotropic drugs ; psychotropic medication</subject><ispartof>International journal of geriatric psychiatry, 2015-06, Vol.30 (6), p.580-586</ispartof><rights>Copyright © 2014 John Wiley &amp; Sons, Ltd.</rights><rights>Copyright Wiley Subscription Services, Inc. Jun 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5577-f3e301c8fc7b1f7f49738102ba3e0421e2cef969ea16f92bd5bfb01daf4f1a5f3</citedby><cites>FETCH-LOGICAL-c5577-f3e301c8fc7b1f7f49738102ba3e0421e2cef969ea16f92bd5bfb01daf4f1a5f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25116369$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maust, Donovan T.</creatorcontrib><creatorcontrib>Chen, Shirley H.</creatorcontrib><creatorcontrib>Benson, Amy</creatorcontrib><creatorcontrib>Mavandadi, Shahrzad</creatorcontrib><creatorcontrib>Streim, Joel E.</creatorcontrib><creatorcontrib>DiFilippo, Suzanne</creatorcontrib><creatorcontrib>Snedden, Thomas M.</creatorcontrib><creatorcontrib>Oslin, David W.</creatorcontrib><title>Older adults recently started on psychotropic medication: where are the symptoms?</title><title>International journal of geriatric psychiatry</title><addtitle>Int J Geriatr Psychiatry</addtitle><description>Objective The objective of this study is to understand the characteristics of older adults on newly prescribed psychotropic medication with minimal psychiatric symptoms. Methods Naturalistic cohort study of non‐institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assistance Contract for the Elderly. Persons newly prescribed antidepressant or anxiolytic monotherapy or combination therapy were contacted for clinical assessment by a telephone‐based behavioral health service. The initial assessment included standardized mental health screening instruments and scales including the Blessed Orientation‐Memory‐Concentration test, Patient Health Questionnaire‐9, Generalized Anxiety Disorder‐7, and Medical Outcomes Survey (SF‐12). In addition, patients were asked for their understanding of the prescription indication. Results Of the 254 participants who met minimal symptom criteria (Patient Health Questionnaire‐9 &lt; 5 and Generalized Anxiety Disorder‐7 &lt; 5), women comprised slightly more of the anxiolytic compared with antidepressant monotherapy group (88.9% vs. 76.7%, p = 0.04). The most common self‐reported reason for prescription of an antidepressant or anxiolytic was depression or anxiety, respectively, despite near‐absence of these symptoms on clinical assessment. Comparing monotherapy to combination therapy groups, those with combination therapy were more likely to report a history of depression (12.6% vs. 1.8%, p &lt; 0.001) and also report depression as the reason for the prescription (40.2% vs. 21.0%, p &lt; 0.01). Conclusions In this sample of older adults on new psychotropic medication with minimal psychiatric symptoms, there are few patient characteristics that distinguish those on antidepressant versus anxiolytic monotherapy or those on monotherapy versus combination therapy. While quality of care in late‐life mental health has focused on improving detection and treatment, there should be further attention to low‐symptom patients potentially receiving inappropriate pharmacotherapy. Copyright © 2014 John Wiley &amp; Sons, Ltd.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Anxiety Agents - therapeutic use</subject><subject>Antidepressive Agents - therapeutic use</subject><subject>Anxiety Disorders - drug therapy</subject><subject>Cohort Studies</subject><subject>Community health care</subject><subject>Depressive Disorder - drug therapy</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Geriatric psychiatry</subject><subject>Geriatric psychology</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>Health Status</subject><subject>Humans</subject><subject>Male</subject><subject>Mental Disorders - diagnosis</subject><subject>Mental Disorders - drug therapy</subject><subject>Mental health care</subject><subject>Middle Aged</subject><subject>older adults</subject><subject>Older people</subject><subject>Pennsylvania</subject><subject>primary care</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychotropic drugs</subject><subject>psychotropic medication</subject><issn>0885-6230</issn><issn>1099-1166</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqN0V2L1DAUBuAgijuugr9AAt540zUn6Ufqjeiiozi4fg94E9L0xOlu29QkZe2_N8OOKwjCXoRzkYcXznkJeQjsBBjjT39M4SQHWd0iK2B1nQGU5W2yYlIWWckFOyL3QjhnLP2BvEuOeJGEKOsV-XjWt-ipbuc-BurR4Bj7hYaofcSWupFOYTE7F72bOkMHbDujY-fGZ_Ryhx6pTi_ukIZlmKIbwvP75I7VfcAHh3lMvr5-9eX0TbY5W789fbHJTFFUVWYFCgZGWlM1YCub15WQwHijBbKcA3KDti5r1FDamjdt0diGQattbkEXVhyTJ1e5k3c_ZwxRDV0w2Pd6RDcHBWVdgJRp5RtQKUTB8vxGlIHkkvFEH_9Dz93sx7TzXvGa5ZWEv4HGuxA8WjX5btB-UcDUvjyVylP78hJ9dAicm3Toa_inrQSyK3DZ9bj8N0itP3w-BB58FyL-uvbaX6iyElWhtu_X6tN2_e3l9807tRW_AZvZscY</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Maust, Donovan T.</creator><creator>Chen, Shirley H.</creator><creator>Benson, Amy</creator><creator>Mavandadi, Shahrzad</creator><creator>Streim, Joel E.</creator><creator>DiFilippo, Suzanne</creator><creator>Snedden, Thomas M.</creator><creator>Oslin, David W.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope></search><sort><creationdate>201506</creationdate><title>Older adults recently started on psychotropic medication: where are the symptoms?</title><author>Maust, Donovan T. ; Chen, Shirley H. ; Benson, Amy ; Mavandadi, Shahrzad ; Streim, Joel E. ; DiFilippo, Suzanne ; Snedden, Thomas M. ; Oslin, David W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5577-f3e301c8fc7b1f7f49738102ba3e0421e2cef969ea16f92bd5bfb01daf4f1a5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Anxiety Agents - therapeutic use</topic><topic>Antidepressive Agents - therapeutic use</topic><topic>Anxiety Disorders - drug therapy</topic><topic>Cohort Studies</topic><topic>Community health care</topic><topic>Depressive Disorder - drug therapy</topic><topic>Drug therapy</topic><topic>Female</topic><topic>Geriatric psychiatry</topic><topic>Geriatric psychology</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>Health Status</topic><topic>Humans</topic><topic>Male</topic><topic>Mental Disorders - diagnosis</topic><topic>Mental Disorders - drug therapy</topic><topic>Mental health care</topic><topic>Middle Aged</topic><topic>older adults</topic><topic>Older people</topic><topic>Pennsylvania</topic><topic>primary care</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychotropic drugs</topic><topic>psychotropic medication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maust, Donovan T.</creatorcontrib><creatorcontrib>Chen, Shirley H.</creatorcontrib><creatorcontrib>Benson, Amy</creatorcontrib><creatorcontrib>Mavandadi, Shahrzad</creatorcontrib><creatorcontrib>Streim, Joel E.</creatorcontrib><creatorcontrib>DiFilippo, Suzanne</creatorcontrib><creatorcontrib>Snedden, Thomas M.</creatorcontrib><creatorcontrib>Oslin, David W.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><jtitle>International journal of geriatric psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maust, Donovan T.</au><au>Chen, Shirley H.</au><au>Benson, Amy</au><au>Mavandadi, Shahrzad</au><au>Streim, Joel E.</au><au>DiFilippo, Suzanne</au><au>Snedden, Thomas M.</au><au>Oslin, David W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Older adults recently started on psychotropic medication: where are the symptoms?</atitle><jtitle>International journal of geriatric psychiatry</jtitle><addtitle>Int J Geriatr Psychiatry</addtitle><date>2015-06</date><risdate>2015</risdate><volume>30</volume><issue>6</issue><spage>580</spage><epage>586</epage><pages>580-586</pages><issn>0885-6230</issn><eissn>1099-1166</eissn><coden>IJGPES</coden><abstract>Objective The objective of this study is to understand the characteristics of older adults on newly prescribed psychotropic medication with minimal psychiatric symptoms. Methods Naturalistic cohort study of non‐institutionalized older adults in Pennsylvania participating in the Pharmaceutical Assistance Contract for the Elderly. Persons newly prescribed antidepressant or anxiolytic monotherapy or combination therapy were contacted for clinical assessment by a telephone‐based behavioral health service. The initial assessment included standardized mental health screening instruments and scales including the Blessed Orientation‐Memory‐Concentration test, Patient Health Questionnaire‐9, Generalized Anxiety Disorder‐7, and Medical Outcomes Survey (SF‐12). In addition, patients were asked for their understanding of the prescription indication. Results Of the 254 participants who met minimal symptom criteria (Patient Health Questionnaire‐9 &lt; 5 and Generalized Anxiety Disorder‐7 &lt; 5), women comprised slightly more of the anxiolytic compared with antidepressant monotherapy group (88.9% vs. 76.7%, p = 0.04). The most common self‐reported reason for prescription of an antidepressant or anxiolytic was depression or anxiety, respectively, despite near‐absence of these symptoms on clinical assessment. Comparing monotherapy to combination therapy groups, those with combination therapy were more likely to report a history of depression (12.6% vs. 1.8%, p &lt; 0.001) and also report depression as the reason for the prescription (40.2% vs. 21.0%, p &lt; 0.01). Conclusions In this sample of older adults on new psychotropic medication with minimal psychiatric symptoms, there are few patient characteristics that distinguish those on antidepressant versus anxiolytic monotherapy or those on monotherapy versus combination therapy. While quality of care in late‐life mental health has focused on improving detection and treatment, there should be further attention to low‐symptom patients potentially receiving inappropriate pharmacotherapy. Copyright © 2014 John Wiley &amp; Sons, Ltd.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>25116369</pmid><doi>10.1002/gps.4187</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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ispartof International journal of geriatric psychiatry, 2015-06, Vol.30 (6), p.580-586
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source Wiley-Blackwell Read & Publish Collection
subjects Aged
Aged, 80 and over
Anti-Anxiety Agents - therapeutic use
Antidepressive Agents - therapeutic use
Anxiety Disorders - drug therapy
Cohort Studies
Community health care
Depressive Disorder - drug therapy
Drug therapy
Female
Geriatric psychiatry
Geriatric psychology
Health Knowledge, Attitudes, Practice
Health Status
Humans
Male
Mental Disorders - diagnosis
Mental Disorders - drug therapy
Mental health care
Middle Aged
older adults
Older people
Pennsylvania
primary care
Psychiatric Status Rating Scales
Psychotropic drugs
psychotropic medication
title Older adults recently started on psychotropic medication: where are the symptoms?
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