Wilforcidine, a New Alkaloid from Tripterygium wilfordii

A new dihydroagarofuran sesquiterpene alkaloid with a trans-cinnamoyloxy group at the C-8 position was isolated from Tripterygium wilfordii. Its structure was elucidated by spectral analysis, including 2D nmr DQF-COSY, HMBC, and NOESY spectra.

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1994-02, Vol.57 (2), p.305-307
Main Authors: He, Zhi-Sheng, Wu, Hou-Ming, Niwa, Masatake, Hirata, Yoshimasa
Format: Article
Language:English
Subjects:
AGENTES ANTINEOPLASTICOS
ALCALOIDE
ALCALOIDES
ALKALOIDS
ANTINEOPLASTIC AGENTS
Biological and medical sciences
CELASTRACEAE
CHEMICAL COMPOSITION
CHINA
CHINE
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
ESPECTROMETRIA
General pharmacology
Medical sciences
MEDICAMENT CYTOSTATIQUE
MOLECULAR CONFORMATION
MOLECULAR STRUCTURE
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
SESQUITERPENES
SESQUITERPENOIDE
SESQUITERPENOIDS
SESQUITERPENOS
SPECTRAL ANALYSIS
SPECTROMETRIE
SPECTROMETRY
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Description
Summary:A new dihydroagarofuran sesquiterpene alkaloid with a trans-cinnamoyloxy group at the C-8 position was isolated from Tripterygium wilfordii. Its structure was elucidated by spectral analysis, including 2D nmr DQF-COSY, HMBC, and NOESY spectra.
ISSN:0163-3864
1520-6025
DOI:10.1021/np50104a018