Surgical treatment of esophageal cancer : Evolution of management and prognosis over the last 3 decades

An increasing incidence of adenocarcinoma, a modified surgical strategy and the increasing use of multimodal therapeutic protocols have had a major impact on the surgical treatment of esophageal cancer during the last 3 decades. This study analyzed the development of these factors and their impact o...

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Bibliographic Details
Published in:Chirurg 2015-07, Vol.86 (7), p.662-669
Main Authors: Glatz, T, Marjanovic, G, Zirlik, K, Brunner, T, Hopt, U T, Makowiec, F, Hoeppner, J
Format: Article
Language:ger
Subjects:
Adenocarcinoma - mortality
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Aged
Analgesia, Epidural - trends
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Chemoradiotherapy, Adjuvant - trends
Combined Modality Therapy - trends
Esophageal Neoplasms - mortality
Esophageal Neoplasms - pathology
Esophageal Neoplasms - surgery
Esophagectomy - trends
Female
Humans
Laparoscopy - trends
Male
Middle Aged
Neoplasm Staging
Postoperative Complications - etiology
Postoperative Complications - mortality
Prognosis
Retrospective Studies
Survival Rate - trends
Thoracotomy - trends
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Summary:An increasing incidence of adenocarcinoma, a modified surgical strategy and the increasing use of multimodal therapeutic protocols have had a major impact on the surgical treatment of esophageal cancer during the last 3 decades. This study analyzed the development of these factors and their impact on the short and long-term prognosis of esophageal cancer over the last 25 years. The study included 366 patients with esophageal cancer treated by esophagectomy at the University Hospital in Freiburg from 1988 to 2012. The study period was split into four time periods for further comparisons, i.e. 1988-1994, 1995-2001, 2001-2006 and 2007-2012. Within the time periods analyzed a marked increase in adenocarcinoma was found (time periods1988-1994, 1995-2001, 2001-2006 and 2007-2012: 21%, 37%, 61% and 64%, respectively, p
ISSN:1433-0385
DOI:10.1007/s00104-014-2877-9