The Prognostic Impact of Tumor Size on Cancer-Specific and Overall Survival Among Patients With Pathologic T3a Renal Cell Carcinoma

Micro-Abstract One third of patients are currently diagnosed with locally advanced renal cell carcinoma (RCC). We evaluated the prognostic role of tumor dimension among patients with stage pT3a RCC. Patients with tumor size > 8 cm showed a 3.65-fold higher risk of cancer-specific mortality compar...

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Bibliographic Details
Published in:Clinical genitourinary cancer 2015-08, Vol.13 (4), p.e235-e241
Main Authors: Schiavina, Riccardo, Borghesi, Marco, Chessa, Francesco, Dababneh, Hussam, Bianchi, Lorenzo, Della Mora, Livia, Del Prete, Chiara, Longhi, Barbara, Rizzi, Simona, Fiorentino, Michelangelo, Martorana, Giuseppe, Brunocilla, Eugenio
Format: Article
Language:English
Subjects:
Aged
Carcinoma, Renal Cell - pathology
Female
Hematology, Oncology and Palliative Medicine
Humans
Kidney Neoplasms - pathology
Locally advanced renal cell carcinoma
Male
Middle Aged
Neoplasm Grading
Prognosis
Prospective Studies
Radical nephrectomy
Survival
Survival Analysis
TNM classification
Tumor Burden
Tumor dimension
Urology
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Summary:Micro-Abstract One third of patients are currently diagnosed with locally advanced renal cell carcinoma (RCC). We evaluated the prognostic role of tumor dimension among patients with stage pT3a RCC. Patients with tumor size > 8 cm showed a 3.65-fold higher risk of cancer-specific mortality compared with those with a stage pT3a RCC tumor ≤ 8 cm ( P  < .001). Tumor size should be taken into account in future revisions of the tumor, node, metastasis (TNM) staging system.
ISSN:1558-7673
1938-0682
DOI:10.1016/j.clgc.2014.06.011