Manoalide-related Sesterterpene from the Marine Sponge Luffariella variabilis

A new manoalide-related sesterterpene, (4E,6E)-dehydro-25-O-methylmanoalide (1), was isolated from the organic extracts of the Bornean marine sponge Luffariella variabilis, together with the known compound (4E,6E)-dehydromanoalide (2). The structure of compound 1 was elucidated by interpretation of...

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Bibliographic Details
Published in:Natural product communications 2015-06, Vol.10 (6), p.863-864
Main Authors: Hamada, Toshiyuki, Harada, Daisuke, Hirata, Mitsunobu, Yamashita, Keisuke, Palaniveloo, Kishneth, Okamura, Hiroaki, Iwagawa, Tetsuo, Arima, Naomichi, Iriguchi, Toshiyuki, de Voogd, Nicole J., Vairappan, Charles S.
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - chemistry
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
Cell Line, Tumor
Cell Survival - drug effects
Humans
Molecular Structure
Porifera - chemistry
Sesterterpenes - chemistry
Sesterterpenes - isolation & purification
Sesterterpenes - pharmacology
Terpenes - chemistry
Terpenes - isolation & purification
Terpenes - pharmacology
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Summary:A new manoalide-related sesterterpene, (4E,6E)-dehydro-25-O-methylmanoalide (1), was isolated from the organic extracts of the Bornean marine sponge Luffariella variabilis, together with the known compound (4E,6E)-dehydromanoalide (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1501000616