Carotid plaque elasticity estimation using ultrasound elastography, MRI, and inverse FEA – A numerical feasibility study

Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be...

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Bibliographic Details
Published in:Medical engineering & physics 2015-08, Vol.37 (8), p.801-807
Main Authors: Nieuwstadt, H.A, Fekkes, S, Hansen, H.H.G, de Korte, C.L, van der Lugt, A, Wentzel, J.J, van der Steen, A.F.W, Gijsen, F.J.H
Format: Article
Language:English
Subjects:
Biomechanical modeling
Carotid Artery Diseases - diagnostic imaging
Carotid Artery Diseases - pathology
Carotid atherosclerosis
Computer Simulation
Elasticity estimation
Elasticity Imaging Techniques - methods
Feasibility Studies
Finite Element Analysis
Humans
Inverse problem
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Models, Cardiovascular
Nonlinear Dynamics
Plaque, Atherosclerotic - diagnostic imaging
Plaque, Atherosclerotic - pathology
Radiology
Ultrasound elastography
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Summary:Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be to apply our method in vivo.
ISSN:1350-4533
1873-4030
DOI:10.1016/j.medengphy.2015.06.003