Corrosion resistance of Ti modified by chitosan–gold nanoparticles for orthopedic implantation

Highly uniform bionanocomposite film composed of chitosan (CS) and gold nanoparticles (AuNPs) was synthesized successfully by electrodeposition method. The influence of AuNPs/CS bionanocomposite film on corrosion resistance of Ti was investigated. Surface morphology and compositional properties of t...

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Bibliographic Details
Published in:International journal of biological macromolecules 2015-08, Vol.79, p.787-799
Main Authors: Farghali, R.A., Fekry, A.M., Ahmed, Rasha A., Elhakim, H.K.A.
Format: Article
Language:English
Subjects:
Adsorption
Animals
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
AuNPs
Chitosan
Chitosan - chemistry
Chitosan - pharmacology
Coated Materials, Biocompatible
Corrosion
Electrochemical Techniques
Gold - chemistry
Gold - pharmacology
Humans
Materials Testing
Metal Nanoparticles - chemistry
Metal Nanoparticles - ultrastructure
Nanocomposites - chemistry
Nanocomposites - ultrastructure
Prostheses and Implants
Staphylococcus aureus - drug effects
Staphylococcus aureus - growth & development
Surface Properties
Titanium
Titanium - chemistry
Titanium - pharmacology
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Summary:Highly uniform bionanocomposite film composed of chitosan (CS) and gold nanoparticles (AuNPs) was synthesized successfully by electrodeposition method. The influence of AuNPs/CS bionanocomposite film on corrosion resistance of Ti was investigated. Surface morphology and compositional properties of the bionanocomposite were analyzed by scanning electron microscope (SEM), energy dispersive X-ray analysis (EDX), and X-ray photoelectron spectroscopy (XPS). Moreover, cyclic voltammetry (CV), open-circuit potential measurements (OCP), electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization (Rp) were used to examine the corrosion behavior in Hanks’ solution. In comparison with Ti, Nyquist and Bode plots displayed higher impedance values and phase angles for AuNPs/CS biocomposite denoting a more protective passive film on Ti with inhibition efficiency (IE%) of 98%. An electric equivalent circuit with three time constants was modeled for the bionanocomposite. In addition, the antibacterial effect revealed the high efficiencies of the bionanocomposite film for inhibiting bacterial growth. The combination of the high biocompatibility of chitosan and strong adsorption ability of AuNPs make AuNPs/CS bionanocomposite promising candidate for modifying biomaterial surfaces for medical implantation applications.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2015.04.078