Intranasal dexmedetomidine for sedation in children undergoing transthoracic echocardiography study-a prospective observational study

Summary Background Intranasal dexmedetomidine has been used for sedation in children undergoing nonpainful procedures. Objective The aim of this study was to determine the success rate of intranasal dexmedetomidine sedation for children undergoing transthoracic echocardiography examination. Methods...

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Bibliographic Details
Published in:Pediatric anesthesia 2015-09, Vol.25 (9), p.891-896
Main Authors: Li, Bi L., Ni, Jin, Huang, Jun X., Zhang, Na, Song, Xing R., Yuen, Vivian M.
Format: Article
Language:English
Subjects:
Administration, Intranasal
Anesthesia Recovery Period
Blood Pressure - drug effects
Child, Preschool
Dexmedetomidine - administration & dosage
echocardiogram
Echocardiography
Female
Heart Rate - drug effects
Humans
Hypnotics and Sedatives - administration & dosage
Infant
Male
nasal
nonpainful procedure
pediatric
Prospective Studies
sedative
Time Factors
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Summary:Summary Background Intranasal dexmedetomidine has been used for sedation in children undergoing nonpainful procedures. Objective The aim of this study was to determine the success rate of intranasal dexmedetomidine sedation for children undergoing transthoracic echocardiography examination. Methods This was a prospective observational study of 115 children under the age of 3 years undergoing echocardiography examination under sedation with intranasal dexmedetomidine at 3 mcg·kg−1. Results Of the 115 children, 100 (87%) had satisfactory sedation with intranasal dexmedetomidine. The mean onset time was 16.7 ± 7 min (range 5–50 min). The mean wake up time was 44.3 ± 15.1 min (range 12–123 min). The wake up time was significantly correlated with duration of procedure with R = 0.540 (P 
ISSN:1155-5645
1460-9592
DOI:10.1111/pan.12687