Postexposure Rabies Vaccination During Pregnancy: Effect on 202 Women and Their Infants

This prospective study of 202 pregnant Thai women who received postexposure treatment for rabies with a tissue culture-derived rabies vaccine and human or equine rabies immune globulin revealed an adverse reaction rate similar to that seen among nonpregnant Thai patients who received the same treatm...

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Bibliographic Details
Published in:Clinical infectious diseases 1995-04, Vol.20 (4), p.818-820
Main Authors: Chutivongse, Supawat, Wilde, Henry, Benjavongkulchai, Maneerat, Chomchey, Pranee, Punthawong, Saluay
Format: Article
Language:English
Subjects:
Adult
Animals
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Bites and Stings
Clinical Articles
Dogs
Female
Follow-Up Studies
Horses
Human bacterial diseases
Humans
Immunoglobulins
Infant, Newborn
Infectious diseases
Injection sites
Medical sciences
Nonprofit organizations
Pregnancy
Pregnancy Outcome
Prospective Studies
Rabies
Rabies vaccines
Rabies Vaccines - administration & dosage
Rabies Vaccines - adverse effects
rabies virus
Symptoms
Tissue culture techniques
Vaccination
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Summary:This prospective study of 202 pregnant Thai women who received postexposure treatment for rabies with a tissue culture-derived rabies vaccine and human or equine rabies immune globulin revealed an adverse reaction rate similar to that seen among nonpregnant Thai patients who received the same treatment. Tissue culture-derived rabies vaccines as well as immune globulins are safe to use for postexposure prophylaxis during pregnancy. Such treatment should never be withheld or delayed if the patient possibly was exposed to rabies.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/20.4.818