Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process

A cyclic boronate structure was incorporated into Si-rhodamine to design a pH-activatable near-infrared (NIR) probe based on the reversible ring-opening process triggered by H(+). The probe showed general suitability of specific labelling of acidic lysosomes and tracking their pH changes in living c...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2015-01, Vol.51 (47), p.9608-9611
Main Authors: Zhu, Weiwei, Chai, Xiaoyun, Wang, Baogang, Zou, Yan, Wang, Ting, Meng, Qingguo, Wu, Qiuye
Format: Article
Language:English
Subjects:
Animals
Fluorescent Dyes - chemistry
Fluorescent Dyes - metabolism
Hep G2 Cells
Humans
Hydrogen-Ion Concentration
Image Processing, Computer-Assisted - methods
Imaging
Labelling
Lysosomes
Lysosomes - metabolism
Molecular Imaging
PC12 Cells
Rats
Rhodamines - chemistry
Rhodamines - metabolism
Spectrometry, Fluorescence
Spectroscopy, Near-Infrared
Spironolactone - chemistry
Spironolactone - metabolism
Tracking
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A cyclic boronate structure was incorporated into Si-rhodamine to design a pH-activatable near-infrared (NIR) probe based on the reversible ring-opening process triggered by H(+). The probe showed general suitability of specific labelling of acidic lysosomes and tracking their pH changes in living cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc02496j