In Vitro and In Vivo Supramolecular Modification of Biomembranes Using a Lipidated Coiled-Coil Motif

Superficial appeal: The surface of live cells and zebrafish embryos can be modified by a supramolecular method. A peptide pair that forms a coiled coil at the cell membrane can be used to dock liposomes in in vitro and in vivo environments (see scheme). This tool can be used in biophysical studies o...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 2013-12, Vol.52 (52), p.14247-14251
Main Authors: Zope, Harshal R., Versluis, Frank, Ordas, Anita, Voskuhl, Jens, Spaink, Herman P., Kros, Alexander
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Biocompatibility
Biomedical materials
coiled coil
Coiling
Humans
In vitro testing
In vivo testing
In vivo tests
Liposomes - chemistry
Membranes
peptide amphiphiles
Peptides - chemistry
Protein Binding
Protein Structure, Tertiary
self-assembly
supramolecular chemistry
Surgical implants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Superficial appeal: The surface of live cells and zebrafish embryos can be modified by a supramolecular method. A peptide pair that forms a coiled coil at the cell membrane can be used to dock liposomes in in vitro and in vivo environments (see scheme). This tool can be used in biophysical studies of biological processes occurring at membranes.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201306033