Risk factors for depressive symptoms in glaucoma patients: a nationwide case-control study

Purpose The purpose was to investigate the risk factors for depressive symptoms in glaucoma patients. Methods From the Longitudinal Health Insurance Database in Taiwan, we included 1190 glaucoma patients with subsequent depression diagnoses in the case group and randomly selected 4673 glaucoma patie...

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Published in:Graefe's archive for clinical and experimental ophthalmology 2015-08, Vol.253 (8), p.1319-1325
Main Authors: Su, Chien-Chia, Chen, Judy Yi-Chu, Wang, Tsing-Hong, Huang, Jehn-Yu, Yang, Chung-May, Wang, I-Jong
Format: Article
Language:English
Subjects:
Adult
Aged
Antihypertensive Agents - therapeutic use
Cardiovascular Diseases - epidemiology
Case-Control Studies
Cerebrovascular Disorders - epidemiology
Comorbidity
Databases, Factual
Depressive Disorder - diagnosis
Depressive Disorder - epidemiology
Diabetes Complications - epidemiology
Female
Glaucoma
Glaucoma - diagnosis
Glaucoma - drug therapy
Glaucoma - epidemiology
Humans
Hypertension - epidemiology
Male
Medicine
Medicine & Public Health
Middle Aged
Odds Ratio
Ophthalmology
Peripheral Vascular Diseases - epidemiology
Risk Factors
Taiwan - epidemiology
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Summary:Purpose The purpose was to investigate the risk factors for depressive symptoms in glaucoma patients. Methods From the Longitudinal Health Insurance Database in Taiwan, we included 1190 glaucoma patients with subsequent depression diagnoses in the case group and randomly selected 4673 glaucoma patients without depression diagnoses as the control group, matched by age, sex, and time of glaucoma diagnosis. The age-adjusted Charlson comorbidity index (ACCI) score was used to compute the burden of comorbidity for each patient. Current use (past 6 months) of topical antiglaucoma medications and systemic medications was identified. Multivariate regression was used to analyze the risk factors for depression. Results The mean age for glaucoma patients was 61.88 years. Patients with depressive symptoms had significantly higher ACCI scores ( P  
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-015-3032-0