Multidetector-row computed tomography for prosthetic heart valve dysfunction: is concomitant non-invasive coronary angiography possible before redo-surgery?

• Published in: European radiology 2015-06, Vol.25 (6), p.1623-1630
• Main Authors: Tanis, Wilco, Suchá, Dominika, Laufer, Ward, Habets, Jesse, van Herwerden, Lex. A., Symersky, Petr, Chamuleau, Steven, Budde, Ricardo P. J.
• Format: Article
• Language: English
• Subjects: Aged; Angioplasty; Cardiac; Cardiology; Cardiovascular disease; Coronary Angiography - methods; Coronary Stenosis - diagnostic imaging; Coronary vessels; Diagnostic Radiology; Embolization; Equipment Failure Analysis - methods; Female; Heart surgery; Heart Valve Prosthesis; Heart Valves - diagnostic imaging; Humans; Imaging; Internal Medicine; Interventional Radiology; Ischemia; Male; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Multidetector Computed Tomography - methods; Neuroradiology; Patients; Preoperative Care - methods; Prostheses; Prosthesis Failure; Radiology; Reoperation; Reproducibility of Results; Teaching hospitals; Tomography; Ultrasound; Vein & artery diseases
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-014-3551-9

Objectives Retrospective ECG-gated multidetector-row computed tomography (MDCT) is increasingly used for the assessment of prosthetic heart valve (PHV) dysfunction, but is also hampered by PHV-related artefacts/cardiac arrhythmias. Furthermore, it is performed without nitroglycerine or heart rate correction. The purpose was to determine whether MDCT performed before potential redo-PHV surgery is feasible for concomitant coronary artery stenosis assessment and can replace invasive coronary angiography (CAG). Methods PHV patients with CAG and MDCT were identified. Based on medical history, two groups were created: (I) patients with no known coronary artery disease (CAD), (II) patients with known CAD. All images were scored for the presence of significant (>50 %) stenosis. CAG was the reference test. Results Fifty-one patients were included. In group I ( n  = 38), MDCT accurately ruled out significant stenosis in 19/38 (50 %) patients, but could not replace CAG in the remaining 19/38 (50 %) patients due to non-diagnostic image quality ( n  = 16) or significant stenosis ( n  = 3) detection. In group II ( n  = 13), MDCT correctly found no patients without significant stenosis, requiring CAG imaging in all. MDCT assessed patency in 16/19 (84 %) grafts and detected a hostile anatomy in two. Conclusion MDCT performed for PHV dysfunction assessment can replace CAG (100 % accurate) in approximately half of patients without previously known CAD. Key Points • Retrospective MDCT is increasingly used for prosthetic heart valve dysfunction assessment • In case of PHV reoperation , invasive coronary angiography is also required • MDCT can replace CAG in 50  % of patients without coronary artery disease • When conclusive for coronary assessment , MDCT stenosis rule out is highly accurate • Replacing CAG saves associated risks of distant embolization of thrombi or vegetations