relationship between hepatitis B virus (HBV) load and levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) in human immunodeficiency virus patients with occult HBV infection

The aim of this study was to evaluate the correlation between hepatitis B virus (HBV) load and serum levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) cytokines in human immunodeficiency virus (HIV) patients who have never been treated with antiretroviral therapy. HBV and h...

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Bibliographic Details
Published in:Archives of virology 2015-07, Vol.160 (7), p.1801-1804
Main Authors: de Almeida Silva, Jéfferson Luis, De Deus, Dayse Maria Vasconcelos, Moreira, Regina Célia, de Morais, Clarice Neuenschwander Lins, Coêlho, Maria Rosângela Cunha Duarte
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adolescent
Adult
Aged
AIDS
antiretroviral agents
Biomedical and Life Sciences
Biomedicine
blood serum
Brief Report
Case-Control Studies
Coinfection - blood
Coinfection - virology
Cytokines
Drug therapy
Fas Ligand Protein - blood
Female
Growth factors
Health sciences
Hepatitis B
Hepatitis B - blood
Hepatitis B - virology
Hepatitis B virus
Hepatitis B virus - genetics
Hepatitis B virus - physiology
Hepatitis C
Hepatitis C virus
HIV
HIV Infections - blood
HIV Infections - virology
HIV-1 - physiology
Human immunodeficiency virus
Human immunodeficiency virus 1
Humans
Immunoassay
Immunology
Infections
Infectious Diseases
Laboratories
Male
Medical Microbiology
Middle Aged
patients
R&D
Research & development
therapeutics
transforming growth factor beta 1
Transforming Growth Factor beta1 - blood
Tumor necrosis factor-TNF
Viral Load
Virology
Young Adult
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Summary:The aim of this study was to evaluate the correlation between hepatitis B virus (HBV) load and serum levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) cytokines in human immunodeficiency virus (HIV) patients who have never been treated with antiretroviral therapy. HBV and hepatitis C virus (HCV) serological markers, sFas and TGF-β1 levels, and HBV load were evaluated in 116 patients. While there was no correlation between TGF-β1 levels and HBV load, a positive correlation between sFas levels and HBV load was observed in patients with occult HBV infection.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-015-2445-8