Lower-limb amputation and body weight changes in men

Little is known about the relationship between lower-limb amputation (LLA) and subsequent changes in body weight. We conducted a retrospective cohort study using clinical and administrative databases to identify and follow weight changes in 759 males with amputation (partial foot amputation [PFA], n...

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Bibliographic Details
Published in:Journal of rehabilitation research and development 2015-01, Vol.52 (2), p.159-170
Main Authors: Littman, Alyson J, Thompson, Mary Lou, Arterburn, David E, Bouldin, Erin, Haselkorn, Jodie K, Sangeorzan, Bruce J, Boyko, Edward J
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Amputation
Body Mass Index
Follow-Up Studies
Humans
Lower Extremity
Male
Middle Aged
Retrospective Studies
Sex Factors
Studies
Weight control
Weight Gain
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Summary:Little is known about the relationship between lower-limb amputation (LLA) and subsequent changes in body weight. We conducted a retrospective cohort study using clinical and administrative databases to identify and follow weight changes in 759 males with amputation (partial foot amputation [PFA], n = 396; transtibial amputation [TTA], n = 267; and transfemoral amputation [TFA], n = 96) and 3,790 nondisabled persons frequency-matched (5:1) on age, body mass index, diabetes, and calendar year from eight Department of Veterans Affairs medical care facilities in the Pacific Northwest. We estimated and compared longitudinal percent weight change from baseline during up to 39 mo of follow-up in participants with and without amputation. Weight gain in the 2 yr after amputation was significantly more in men with an amputation than without, and in men with a TTA or TFA (8%-9% increase) than in men with a PFA (3%-6% increase). Generally, percent weight gain peaked at 2 yr and was followed by some weight loss in the third year. These findings indicate that LLA is often followed by clinically important weight gain. Future studies are needed to better understand the reasons for weight gain and to identify intervention strategies to prevent excess weight gain and the deleterious consequences that may ensue.
ISSN:0748-7711
1938-1352
DOI:10.1682/JRRD.2014.07.0166