Combination of Juvenile Papillomatosis, Juvenile Fibroadenoma and Intraductal Carcinoma of the Breast in a 15-Year-old Girl

The association of juvenile papillomatosis with carcinoma is proven, but very rare, as there exist several reported cases. A 15-year-old girl with no family history of breast cancer presented with two masses in the left breast. The excisional biopsy on both lumps revealed juvenile fibroadenoma and j...

Full description

Saved in:
Bibliographic Details
Published in:Anticancer research 2015-09, Vol.35 (9), p.5027-5029
Main Authors: Sedloev, Theophil, Bassarova, Assia, Angelov, Kostadin, Vasileva, Mariela, Asenov, Yavor
Format: Article
Language:English
Subjects:
Adolescent
Breast - pathology
Breast Neoplasms - complications
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Carcinoma, Intraductal, Noninfiltrating - complications
Carcinoma, Intraductal, Noninfiltrating - diagnostic imaging
Carcinoma, Intraductal, Noninfiltrating - pathology
Female
Fibroadenoma - complications
Fibroadenoma - diagnostic imaging
Fibroadenoma - pathology
Humans
Papilloma - complications
Papilloma - diagnostic imaging
Papilloma - pathology
Ultrasonography
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The association of juvenile papillomatosis with carcinoma is proven, but very rare, as there exist several reported cases. A 15-year-old girl with no family history of breast cancer presented with two masses in the left breast. The excisional biopsy on both lumps revealed juvenile fibroadenoma and juvenile papillomatosis epithelial proliferation multiple cystic expanded channels. In some of these channels, cytological features of intraductal carcinoma were observed. We performed a full immunohistochemical examination of the juvenile papillomatosis. The patient refused any further surgical or adjuvant treatment. There are no signs of recurrence in the 15 year follow-up. This case is a diagnostic and therapeutic challenge, taking into account the patient's age and the controversial treatment recommendations. Good collaboration between surgeons and pathologists is essential for an accurate diagnostic process and aims to avoid under- or overtreatment.
ISSN:1791-7530