Differences between coagulation and cytokine profiles in dogs of different ages

•We compared thromboelastometric profiles between two groups of dogs of distinct ages.•Old dogs exhibited hypercoagulable profiles and decrease in fibrinolytic activity.•Haematocrit and fibrinogen contributed to this hypercoagulability.•This study supports the consideration of age as a risk factor f...

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Bibliographic Details
Published in:The veterinary journal (1997) 2015-09, Vol.205 (3), p.410-412
Main Authors: Barthélemy, A., Rannou, B., Forterre, M., Verwaerde, P., Bonnet-Garin, J.-M., Pouzot-Nevoret, C., Goy-Thollot, I.
Format: Article
Language:English
Subjects:
Ageing
Aging
Animals
Blood Coagulation
Coagulation
Cytokines
Cytokines - blood
Dog
Dogs
Female
Male
Risk Factors
Thrombelastography - veterinary
Thromboelastometry
Thrombosis - etiology
Thrombosis - veterinary
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Summary:•We compared thromboelastometric profiles between two groups of dogs of distinct ages.•Old dogs exhibited hypercoagulable profiles and decrease in fibrinolytic activity.•Haematocrit and fibrinogen contributed to this hypercoagulability.•This study supports the consideration of age as a risk factor for thrombosis in dogs. In human medicine, age is a risk factor for thromboembolic diseases associated with hypercoagulable and antifibrinolytic states, but information in veterinary medicine is limited. This study compared the thromboelastometric (TEM) profiles of two groups of dogs of distinct ages. Ten healthy old (>10 years) Beagles and 10 healthy young (
ISSN:1090-0233
1532-2971
DOI:10.1016/j.tvjl.2015.05.012