Intralesional Bleomycin for Warts: Patient Satisfaction and Treatment Outcomes

Background: The treatment of warts is challenging with regards to both tolerability and efficacy. Objective: Ascertain the efficacy, tolerability, and patient satisfaction of intralesional bleomycin in the treatment of warts. Methods: Retrospective chart review followed by telephone interviews with...

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Bibliographic Details
Published in:Journal of cutaneous medicine and surgery 2015-09, Vol.19 (5), p.470-476
Main Authors: Kruter, Laura, Saggar, Vishal, Akhavan, Alaleh, Patel, Parth, Umanoff, Nicole, Viola, Kate V., Stebbins, William, Smith, Elizabeth, Akhavan, Arash, Cohen, Justine V., Cohen, Steven R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Antibiotics, Antineoplastic - administration & dosage
Bleomycin - administration & dosage
Female
Foot Dermatoses - drug therapy
Hand Dermatoses - drug therapy
Humans
Injections, Intralesional
Male
Middle Aged
Patient Satisfaction
Retrospective Studies
Treatment Outcome
Warts - drug therapy
Young Adult
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Summary:Background: The treatment of warts is challenging with regards to both tolerability and efficacy. Objective: Ascertain the efficacy, tolerability, and patient satisfaction of intralesional bleomycin in the treatment of warts. Methods: Retrospective chart review followed by telephone interviews with patients from university-based dermatology referral centers. Results: Seventy-four percent (34/46) of patients had complete resolution (CR) of all warts. Of 34 patients who experienced CR, an average of 1.7 treatments were required. Pain experienced during the procedure and recovery, irrespective of outcome, was rated 5.8 out of 10 (range, 1-10; SD, 2.72; SEM, 0.40). Approximately 70% of patients had pain that lasted less than 2 days after treatment. Seventy-eight percent (36/46) of patients in the study were satisfied with treatment and would recommend it to others. Conclusion: Patients felt bleomycin to be an effective treatment modality for warts, offering high rates of CR in lesions resistant to more traditional therapies.
ISSN:1203-4754
1615-7109
DOI:10.1177/1203475415576860