Benign chondroblastoma on fine-needle aspiration smears: A seven-case experience and review of the literature

We report seven cases of chondroblastoma (CB) of bone, diagnosed by Fine‐Needle Aspiration Cytology (FNAC), and confirmed by histomorphological examination. The concurrence of some cytomorphologic findings — mononucleated cells, multinucleated cells, and intercellular chondroid substance — unequivoc...

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Bibliographic Details
Published in:Diagnostic cytopathology 2015-09, Vol.43 (9), p.734-738
Main Authors: Cozzolino, Immacolata, Zeppa, Pio, Zabatta, Assunta, Merolla, Francesco, Vetrani, Antonio, Sadile, Francesco
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biopsy, Fine-Needle
Bone and Bones - pathology
bone cytology
Bone Neoplasms - diagnosis
Bone Neoplasms - pathology
bone tumors
Child
chondroblastoma
Chondroblastoma - diagnosis
Chondroblastoma - pathology
Female
fine-needle aspiration cytology
Giant Cell Tumors - diagnosis
Giant Cell Tumors - pathology
Giant Cells - cytology
Humans
Male
Retrospective Studies
Young Adult
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Summary:We report seven cases of chondroblastoma (CB) of bone, diagnosed by Fine‐Needle Aspiration Cytology (FNAC), and confirmed by histomorphological examination. The concurrence of some cytomorphologic findings — mononucleated cells, multinucleated cells, and intercellular chondroid substance — unequivocally suggested the cytological diagnosis of CB. We also reviewed the literature on this topic in order to discuss morphological criteria and the importance of needle size. The differential diagnosis between CB, Giant Cell Tumor of Bone, and Eosinophilic Granuloma is further discussed. Diagn. Cytopathol. 2015;43:734–738. © 2015 Wiley Periodicals, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.23286