Yield of second surveillance colonoscopy to predict adenomas with high-risk characteristics

Abstract Background and aims The yield of surveillance colonoscopies for patients with a history of polyps is well established for first surveillance, but limited for second surveillance. The aim of this study was to evaluate the proportion of high-risk adenomas at second surveillance colonoscopy ba...

Full description

Saved in:
Bibliographic Details
Published in:Digestive and liver disease 2015-09, Vol.47 (9), p.805-810
Main Authors: Laish, Ido, Blechman, Ido, Feingelernt, Haya, Konikoff, Fred M
Format: Article
Language:English
Subjects:
Adenoma - diagnosis
Adenoma - epidemiology
Adult
Aged
Aged, 80 and over
Colon cancer
Colonic Neoplasms - diagnosis
Colonic Neoplasms - epidemiology
Colonic Polyps - pathology
Colonoscopy - methods
Colonoscopy intervals
Early Detection of Cancer
Female
Gastroenterology and Hepatology
High risk adenoma
Humans
Male
Mass Screening
Middle Aged
Retrospective Studies
Risk Assessment
Risk Factors
Surveillance colonoscopy
Tertiary Care Centers
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background and aims The yield of surveillance colonoscopies for patients with a history of polyps is well established for first surveillance, but limited for second surveillance. The aim of this study was to evaluate the proportion of high-risk adenomas at second surveillance colonoscopy based on findings of previous colonoscopies. Methods This retrospective cohort study was conducted in a tertiary hospital and patients who had undergone three colonoscopies were included. Based on the findings at index colonoscopy, patients were categorized into three groups: high-risk adenoma ( n = 252), low-risk adenoma ( n = 158) or no-adenoma ( n = 318). Findings of subsequent high-risk adenoma, low-risk adenoma and no adenoma at surveillance colonoscopies were documented in each group. Results Among patients with high-risk adenoma at index and first surveillance colonoscopies, significantly higher rates of high-risk findings were found at second surveillance, compared with patients who had low-risk or no-adenoma at index colonoscopy and high-risk adenoma at first surveillance colonoscopy (58%, 33% and 10%, respectively, p < 0.001). Conclusions Both index colonoscopy and first surveillance high-risk adenoma have an impact on incidence high-risk findings at second surveillance colonoscopy and these subjects need close surveillance.
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2015.05.005