Cerebral, renal and mesenteric regional oxygen saturation of term infants during transition

Abstract Objective To measure cerebral regional oxygen saturation (CrSO2 ), renal regional oxygenation saturation (RrSO2 ) and mesenteric tissue regional oxygen saturation (MrSO2 ) during immediate transition and continuously for the first 9 hours of age. Fractional tissue oxygen extraction of the b...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pediatric surgery 2015-08, Vol.50 (8), p.1273-1277
Main Authors: Montaldo, Paolo, De Leonibus, Chiara, Giordano, Lucia, De Vivo, Massimiliano, Giliberti, Paolo
Format: Article
Language:English
Subjects:
Biomarkers - metabolism
Brain - metabolism
Cesarean Section
Female
Humans
Infant, Newborn
Kidney - metabolism
Male
Mesentery - metabolism
Near-infrared spectroscopy
Newborn infant
Oxygen - metabolism
Oxygen/blood
Pediatrics
Pregnancy
Prospective Studies
Spectroscopy, Near-Infrared
Splanchnic circulation
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objective To measure cerebral regional oxygen saturation (CrSO2 ), renal regional oxygenation saturation (RrSO2 ) and mesenteric tissue regional oxygen saturation (MrSO2 ) during immediate transition and continuously for the first 9 hours of age. Fractional tissue oxygen extraction of the brain (CtFOE), kidneys (RtFOE), splanchnic tissue (MtFOE) were also assessed. Study design Prospective, observational study of 61 term infants, delivered by elective caesarean section. Using near-infrared spectroscopy, changes in CrSO2 , RrSO2 , MrSO2 and changes in CtFOE, RtFOE and MtFOE were measured all through the first 9 hours of life. All the episodes of feeding during this period were recorded. Results Mean CrSO2 increased quickly to 7 minutes, with no further changes. On the other hand, mean RrSO2 and mean MrSO2 increased for 10 minutes and thereafter they remained on their newly reached level. RrSO2 and MrSO2 were significantly lower at 3-4-5-6-7 minutes of life compared to the CrSO2 ( p < 0.05). RtFOE and MtFOE were significantly higher at 3-4-5-6-7 minutes of life compared to the CtFOE ( p < 0.05). During feeding, CrSO2 , RrSO2 and MrSO2 did not significantly change. Conclusions During early adaptive period, oxygen delivery is preserved to ‘vital’ organs, like brain, at the expense of kidneys and splanchnic tissue. Term infants can provide for the increasing metabolic activity of the intestinal tract during feeding periods without compromising oxygenation.
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2015.04.004