Treatment strategies for severe oligoasthenoteratozoospermia (OAT) (<0.1 million/mL) patients

Summary Intracytoplasmic sperm injection (ICSI) using spermatozoa from patients with severe oligoasthenoteratozoospermia is still a challenge. Although spermatozoa are available, lower fertilisation rates as well as compromised pregnancy rates are observed after ICSI. We aimed at identifying respect...

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Bibliographic Details
Published in:Andrology (Oxford) 2015-09, Vol.3 (5), p.856-863
Main Authors: Nordhoff, V., Fricke, R. K., Schüring, A. N., Zitzmann, M., Kliesch, S.
Format: Article
Language:English
Subjects:
Adult
Asthenozoospermia - therapy
Azoospermia - therapy
Female
Humans
intracytoplasmic sperm injection (ICSI)
Male
oligoasthenoteratozoospermia (OAT)
Pregnancy
Pregnancy Rate
pre‐values
Retrospective Studies
Semen Analysis
Sperm Injections, Intracytoplasmic - methods
Sperm Retrieval
Spermatozoa - physiology
TESE
Testis - physiology
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Summary:Summary Intracytoplasmic sperm injection (ICSI) using spermatozoa from patients with severe oligoasthenoteratozoospermia is still a challenge. Although spermatozoa are available, lower fertilisation rates as well as compromised pregnancy rates are observed after ICSI. We aimed at identifying respective parameters in the pre‐values of ejaculate samples used for couple counselling. The clinical pre‐values of 121 patients and their corresponding 228 ICSI cycles performed between 2002 and 2010 were retrospectively analysed. Patients were divided into three groups: (i) group 1 (G1, n = 51) where all patients showed at least once
ISSN:2047-2919
2047-2927
DOI:10.1111/andr.12077