Carboxylated graphene oxide/polyvinyl chloride as solid-phase extraction sorbent combined with ion chromatography for the determination of sulfonamides in cosmetics

• Published in: Analytica chimica acta 2015-08, Vol.888, p.75-84
• Main Authors: Zhong, Zhixiong, Li, Gongke, Luo, Zhibin, Liu, Zhe, Shao, Yijuan, He, Wanwen, Deng, Jianchao, Luo, Xingling
• Format: Article
• Language: English
• Subjects: Anti-acne cosmetics; Carboxylated graphene oxide/polyvinyl chloride; Chromatography, Ion Exchange - methods; Cosmetics - analysis; Graphite - chemistry; Ion chromatography; Limit of Detection; Multi-response optimization; Oxides - chemistry; Polyvinyl Chloride - chemistry; Solid Phase Extraction - methods; Solid-phase extraction; Sulfonamides - isolation & purification; Sulphonamides
• ISSN: 0003-2670; 1873-4324
• DOI: 10.1016/j.aca.2015.06.054

A carboxylated graphene oxide/polyvinyl chloride (CGO/PVC) material was prepared as a sorbent for the selective extraction of sulphonamides from complex sample. After being dispersed in buffer solution, sample was transferred into the prefabricated solid-phase extraction (SPE) column, which integrated extraction and cleanup into one single-step. A multi-response optimization based on the Box-Behnken design was used to optimize factors affecting extraction efficiency. Compared with the commonly commercial sorbents including MCX, WCX and C18, CGO/PVC hybrid material had higher extraction selectivity and capacity to sulphonamides. The limits of detection and quantification for seven target compounds were in the range of 3.4–7.1 μg/L and 11.4–23.7 μg/L, respectively. The self-assembly SPE cartridge was successfully used to enrich seven analytes in anti-acne cosmetics prior to ion chromatography detection with good recoveries of 87.8–102.0% and relative standard deviations of 1.2–6.4%, implying that this method was suitable for routine analysis of cosmetics. [Display omitted] •SPE using carboxylated graphene oxide/polyvinyl chloride as sorbent was proposed.•Graphene oxide was synthesized and modified chemically.•Extraction protocol was systematically optimized with multi-response optimization.•Extraction selectivity was enhanced by introducing carboxyl group into graphene oxide.•Extraction performance of self-assembly column was superior to commercial sorbents.