Autotransplantation of teeth in humans: a systematic review and meta-analysis

Objectives The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. Materials and methods Electronic searches were conducted to identify randomized controlled and pros...

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Bibliographic Details
Published in:Clinical oral investigations 2015-07, Vol.19 (6), p.1157-1179
Main Authors: Almpani, Konstantinia, Papageorgiou, Spyridon N., Papadopoulos, Moschos A.
Format: Article
Language:English
Subjects:
Dentistry
Humans
Medicine
Review
Risk Factors
Tooth - transplantation
Transplantation, Autologous
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Summary:Objectives The aim of this investigation was to assess the currently available evidence concerning the complications and risk factors influencing the outcome of autotransplantation of teeth in humans. Materials and methods Electronic searches were conducted to identify randomized controlled and prospective clinical trials. Risk of bias within studies was assessed with the Downs and Black tool. Random-effects meta-analyses were conducted to pool the adverse event rates and relative risks with their 95 % confidence intervals. Risk of bias across studies was assessed with the GRADE framework followed by sensitivity analyses. Results Thirty-eight studies were included in the analysis. Reported complications included the need for extraction, failure, hypermobility, pulp necrosis, pulp obliteration, and root resorption. Pooled complication event rates varied considerably, with small studies (
ISSN:1432-6981
1436-3771
DOI:10.1007/s00784-015-1473-9