Specific IgG for cat allergens in patients with allergic conjunctivitis

Immunoglobulin G (IgG) antibodies are involved in type II and type III hypersensitivity. We evaluated the relation between perennial allergic conjunctivitis and serum levels of specific IgG for cat allergens. A prospective study was conducted in patients with seasonal allergic conjunctivitis (season...

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Bibliographic Details
Published in:International ophthalmology 2015-08, Vol.35 (4), p.575-586
Main Authors: Miyama, Anri, Mimura, Tatsuya, Noma, Hidetaka, Goto, Mari, Kamei, Yuko, Kondo, Aki, Saito, Yusuke, Okuma, Hiroko, Matsubara, Masao
Format: Article
Language:English
Subjects:
Adolescent
Adult
Allergens - immunology
Animals
Case-Control Studies
Cats
Child
Child, Preschool
Conjunctivitis, Allergic - diagnosis
Conjunctivitis, Allergic - immunology
Cross-Sectional Studies
Female
Humans
Immunoglobulin E - analysis
Immunoglobulin E - immunology
Immunoglobulin G - blood
Male
Medicine
Medicine & Public Health
Middle Aged
Ophthalmology
Original Paper
Prospective Studies
Tears - immunology
Young Adult
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Summary:Immunoglobulin G (IgG) antibodies are involved in type II and type III hypersensitivity. We evaluated the relation between perennial allergic conjunctivitis and serum levels of specific IgG for cat allergens. A prospective study was conducted in patients with seasonal allergic conjunctivitis (seasonal group, n  = 10), patients with perennial allergic conjunctivitis (perennial group, n  = 10), and healthy control subjects (control group, n  = 10). Serum levels of specific IgE and IgG for cat allergens and total tear IgE were measured, and a skin prick test was also performed. In addition, a severity score associated with allergic conjunctivitis was calculated (0–30). The positive rates and scores of for total tear IgE, serum cat-specific IgE, and serum cat-specific IgG were all higher in the seasonal and perennial groups than in the control group (all p  
ISSN:0165-5701
1573-2630
DOI:10.1007/s10792-014-9987-8