Lupus – the cold, hard facts

Systemic lupus erythematosus (SLE) is a multisystem chronic disease with a multitude of clinical presentations. We review and synthesize how an environmental insult (exposure to extreme cold for a short duration) and endogenous (antiphospholipid antibody syndrome, SLE vasculitis) insults in a suscep...

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Bibliographic Details
Published in:Lupus 2014-07, Vol.23 (8), p.837-839
Main Authors: Wong, NWK, Ng, VT-Y, Ibrahim, S, Slessarev, M, Chandran, V
Format: Article
Language:English
Subjects:
Adult
Cold Temperature - adverse effects
Female
Foot - pathology
Frostbite - etiology
Gangrene - etiology
Humans
Lupus Erythematosus, Systemic - complications
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Summary:Systemic lupus erythematosus (SLE) is a multisystem chronic disease with a multitude of clinical presentations. We review and synthesize how an environmental insult (exposure to extreme cold for a short duration) and endogenous (antiphospholipid antibody syndrome, SLE vasculitis) insults in a susceptible young female with lupus (peripheral arterial disease, smoking, SLE) led to a perfect storm resulting in catastrophic injuries (frostbite).
ISSN:0961-2033
1477-0962
DOI:10.1177/0961203314530485