Everolimus treatment of a newborn with rhabdomyoma causing severe arrhythmia

Rhabdomyoma is the most common cardiac tumour in children often associated with tuberous sclerosis. Arrhythmia caused by cardiac rhabdomyomas may be the initial sign of tuberous sclerosis. Rhabdomyomas unresponsive to other treatments could be successfully managed with everolimus, which has demonstr...

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Bibliographic Details
Published in:Cardiology in the young 2015-10, Vol.25 (7), p.1411-1414
Main Authors: Öztunç, Funda, Atik, Sezen U., Güneş, Aslı O.
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Arrhythmias, Cardiac - etiology
Brief Reports
Echocardiography
Electrocardiography
Everolimus - therapeutic use
Female
Heart Neoplasms - diagnosis
Heart Neoplasms - drug therapy
Humans
Infant, Newborn
Rhabdomyoma - diagnosis
Rhabdomyoma - drug therapy
Tuberous Sclerosis - complications
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Summary:Rhabdomyoma is the most common cardiac tumour in children often associated with tuberous sclerosis. Arrhythmia caused by cardiac rhabdomyomas may be the initial sign of tuberous sclerosis. Rhabdomyomas unresponsive to other treatments could be successfully managed with everolimus, which has demonstrated benefit in tuberous sclerosis. We report a case of rhabdomyoma causing severe arrhythmia in a newborn managed successfully with everolimus.
ISSN:1047-9511
1467-1107
DOI:10.1017/S1047951114002261