SERS detection of low-concentration adenosine by silver nanoparticles on silicon nanoporous pyramid arrays structure

• Published in: Applied surface science 2015-08, Vol.347, p.668-672
• Main Authors: Zhang, C., Man, B.Y., Jiang, S.Z., Yang, C., Liu, M., Chen, C.S., Xu, S.C., Qiu, H.W., Li, Z.
• Format: Article
• Language: English
• Subjects: Adenosine; Adenosines; Arrays; Nanoparticles; Nanostructure; Pyramid; Pyramids; Raman spectroscopy; SERS; Silicon substrates; Silver
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2015.04.170

•We introduce a simple and lost-cost method to achieve the Ag/PS SERS substrate with novel nanoporous pyramid arrays structure.•Detection of low-concentration adenosine (10−7M) is obtained with the Ag/PS SERS substrate.•A reasonable linear correlation is obtained between the intensity of SERS signal and the adenosine concentration from 10−2 to 10−7M in log scale.•The enhancement effect of 0.1, 0.5, 1 Ag/PS is also discussed in detail. A novel surface-enhanced Raman spectroscopy (SERS) substrate based on uniform silver nanoparticles/silicon nanoporous pyramid arrays (Ag/PS) is prepared and SERS behaviors to adenosine are discussed and compared. With a low concentration of 10−7M, the characteristic Raman bands of adenosine demonstrate the significantly high SERS sensitivity of the prepared Ag/PS substrate. A reasonable linear correlation is obtained between the intensity of SERS signal and the adenosine concentration from 10−2 to 10−7M in log scale. These results imply that the Ag/PS with regular pyramids array might be an effective substrate for performing label-free sensitive SERS detections of biomolecule.