Directed Nerve Regeneration Enabled by Wirelessly Powered Electrodes Printed on a Biodegradable Polymer

Wirelessly directed nerve regeneration: inductively powered electrical stimulation circuits on the biodegradable polymer polycaprolactone demonstrate directed regeneration of sensory neurons from a dorsal root ganglion. These circuits, produced using a unique transfer printing process, illustrate pr...

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Bibliographic Details
Published in:Advanced healthcare materials 2014-07, Vol.3 (7), p.1001-1006
Main Authors: Martin, Christopher, Dejardin, Théophile, Hart, Andrew, Riehle, Mathis O., Cumming, David R. S.
Format: Article
Language:English
Subjects:
Absorbable Implants
Animals
Axons - physiology
Biodegradability
biodegradable electronics
Biological and medical sciences
Circuits
electrical stimulation of neurons
Electrodes
Equipment Design
flexible electronics
Ganglia, Spinal - cytology
Medical sciences
micro transfer printing
Nerve Regeneration - physiology
Nerves
Neurons
Neurosurgery
peripheral nerve repair
Polycaprolactone
Polyesters
Rats
Rats, Sprague-Dawley
Regeneration
Stimulation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
Wireless Technology - instrumentation
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Summary:Wirelessly directed nerve regeneration: inductively powered electrical stimulation circuits on the biodegradable polymer polycaprolactone demonstrate directed regeneration of sensory neurons from a dorsal root ganglion. These circuits, produced using a unique transfer printing process, illustrate progress towards the use of electrical stimulation systems on biodegradable materials to improve peripheral nerve repair functional outcomes.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201300481