From Soft Self-Healing Gels to Stiff Films in Suckerin-Based Materials Through Modulation of Crosslink Density and [beta]-Sheet Content

Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapas...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2015-07, Vol.27 (26), p.3953-3961
Main Authors: Ding, Dawei, Guerette, Paul A, Fu, Jing, Zhang, Lihong, Irvine, Scott A, Miserez, Ali
Format: Article
Language:English
Subjects:
Biomedical materials
Blocking
Crosslinking
Density
Elasticity
Modulation
Modulus of elasticity
Recombinant
Online Access:Get full text
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Summary:Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapascal range. The elasticity is controlled by the interplay between the [beta]-sheet content and induced di-tyrosine crosslinking.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201500280