Modulating role of NO in haloperidol-induced catalepsy

Injection of haloperidol during catalepsy modeling decreased the content of NO in rat cerebral cortex. NO precursor L-arginine arrested catalepsy and prevented the decrease in NO content.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2005-03, Vol.139 (3), p.328-330
Main Authors: Narkevich, V B, Mikoyan, V D, Bashkatova, V G
Format: Article
Language:English
Subjects:
Animals
Arginine - pharmacology
Arginine - therapeutic use
Catalepsy - chemically induced
Catalepsy - drug therapy
Catalepsy - prevention & control
Cerebral Cortex - chemistry
Electron Spin Resonance Spectroscopy
Haloperidol
Nitric Oxide - analysis
Nitric Oxide - metabolism
Rats
Time Factors
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Description
Summary:Injection of haloperidol during catalepsy modeling decreased the content of NO in rat cerebral cortex. NO precursor L-arginine arrested catalepsy and prevented the decrease in NO content.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-005-0285-3