Telangiectasia as a potential clinical marker of microvascular lesions in systemic sclerosis patients from EUSTAR data in China

To investigate the prevalence and clinical relevance of telangiectasia in Chinese patients with systemic sclerosis (SSc). Data from 230 SSc EUSTAR patients from Peking Union Medical College Hospital (2009-2011) that fulfilled the 1980 American College of Rheumatology SSc classification criteria were...

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Bibliographic Details
Published in:Clinical and experimental rheumatology 2015-07, Vol.33 (4 Suppl 91), p.S106-S110
Main Authors: Zhang, Shang-zhu, Xu, Dong, Li, Meng-tao, Hou, Yong, Wang, Qian, Tian, Zhuang, Liu, Yong-tai, Guo, Xiao-xiao, Lai, Jin-zhi, Zhao, Jiu-liang, Hu, Chao-jun, Song, Ning, Sun, Qiu-ning, Zhang, Feng-chun, Zhao, Yan, Zeng, Xiao-feng
Format: Article
Language:English
Subjects:
Adult
China - epidemiology
Databases, Factual
Female
Humans
Hypertension, Pulmonary - diagnosis
Hypertension, Pulmonary - epidemiology
Male
Microvessels - pathology
Microvessels - physiopathology
Middle Aged
Predictive Value of Tests
Prevalence
Prognosis
Prospective Studies
Risk Factors
Scleroderma, Systemic - diagnosis
Scleroderma, Systemic - epidemiology
Scleroderma, Systemic - pathology
Scleroderma, Systemic - physiopathology
Skin - blood supply
Skin Ulcer - diagnosis
Skin Ulcer - epidemiology
Skin Ulcer - pathology
Telangiectasis - diagnosis
Telangiectasis - epidemiology
Telangiectasis - pathology
Telangiectasis - physiopathology
Vasodilation
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Summary:To investigate the prevalence and clinical relevance of telangiectasia in Chinese patients with systemic sclerosis (SSc). Data from 230 SSc EUSTAR patients from Peking Union Medical College Hospital (2009-2011) that fulfilled the 1980 American College of Rheumatology SSc classification criteria were prospectively collected. Demographic, clinical, and laboratory data were calculated between groups with and without telangiectasia, and a six-minute walk test, pulmonary function test (PFT), transthoracic echocardiography (TTE), right heart catheterisation (RHC) and modified Rodnan skin score (mRSS) were performed. 96 patients (41.7%) were diagnosed with telangiectasia. There were no significant differences between patients with and without telangiectasia based on gender, age at onset, Raynaud's phenomenon (RP) duration, or SSc classification. Disease duration both from RP onset of patients and from first non-RP manifestation of patients with telangiectasia was significantly longer than patients without (p
ISSN:0392-856X