Effect of African-American Race on Tumor Recurrence After Radical Cystectomy for Urothelial Carcinoma of the Bladder

Micro-Abstract African-American race was found to be independently associated with the recurrence of urothelial carcinoma of the bladder after controlling for established clinical and pathologic characteristics. These data corroborate emerging molecular data, suggesting differences in tumor biology...

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Bibliographic Details
Published in:Clinical genitourinary cancer 2015-10, Vol.13 (5), p.469-475
Main Authors: Paluri, Ravi K, Morgan, Charity J, Mooney, David J, Mgbemena, Okechukwu, Yang, Eddy S, Wei, Shi, Kouba, Erik, Naik, Gurudatta, El Mouallem, Nemer R, Poston, Tyler, Jones, Benjamin, Nix, Jeffrey, Bolger, Graeme B, Deshazo, Mollie, Sonpavde, Guru
Format: Article
Language:English
Subjects:
Adult
African Americans - statistics & numerical data
African-American
Aged
Aged, 80 and over
Bladder cancer
Cystectomy
Female
Hematology, Oncology and Palliative Medicine
Humans
Male
Middle Aged
Neoplasm Recurrence, Local - epidemiology
Prognosis
Radical cystectomy
Recurrence
Risk Factors
United States - ethnology
Urinary Bladder Neoplasms - ethnology
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - surgery
Urology
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Summary:Micro-Abstract African-American race was found to be independently associated with the recurrence of urothelial carcinoma of the bladder after controlling for established clinical and pathologic characteristics. These data corroborate emerging molecular data, suggesting differences in tumor biology according to race and the potential relevance of profiling both host and tumor to discover new therapeutic targets and individualize treatment strategies.
ISSN:1558-7673
1938-0682
DOI:10.1016/j.clgc.2015.02.010