Left Bundle Branch Block in Acute Cardiac Events: Insights From a 23-Year Registry

Between 1991 and 2013, we evaluated the demographics, presentations, and final diagnosis of patients hospitalized with acute cardiac events and left bundle branch block (LBBB). Of 50 992 patients, 768 (1.5%) had LBBB. Compared with non-LBBB patients, patients with LBBB were mostly older, female, dia...

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Bibliographic Details
Published in:Angiology 2015-10, Vol.66 (9), p.811-817
Main Authors: Alkindi, Fahad, El-Menyar, Ayman, Al-Suwaidi, Jassim, Patel, Ashfaq, Gehani, Abdurrazzak A., Singh, Rajvir, Albinali, Hajar, Arabi, Abdulrahman
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Bundle-Branch Block - diagnosis
Bundle-Branch Block - epidemiology
Bundle-Branch Block - mortality
Bundle-Branch Block - therapy
Chi-Square Distribution
Comorbidity
Female
Heart Failure - diagnosis
Heart Failure - epidemiology
Heart Failure - mortality
Heart Failure - therapy
Hospital Mortality
Hospitalization
Humans
Kidney Failure, Chronic - diagnosis
Kidney Failure, Chronic - epidemiology
Logistic Models
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - diagnosis
Myocardial Infarction - epidemiology
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Odds Ratio
Prognosis
Qatar - epidemiology
Registries
Retrospective Studies
Risk Factors
Sex Factors
Time Factors
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Summary:Between 1991 and 2013, we evaluated the demographics, presentations, and final diagnosis of patients hospitalized with acute cardiac events and left bundle branch block (LBBB). Of 50 992 patients, 768 (1.5%) had LBBB. Compared with non-LBBB patients, patients with LBBB were mostly older, female, diabetic, and had hypertension and chronic kidney failure (CKF; P < .001 for all). Dyspnea (P < .001) and dizziness (P = .037) were more frequent in patients with LBBB. The most frequent cause of admission with LBBB was congestive heart failure (CHF; 54.2%), followed by ST-elevation myocardial infarction (STEMI; 13.3%), valvular heart disease (9.4%), unstable angina (8.3%) and Non-STEMI (7.7%). On multivariate analysis, CKF (odds ratio [OR]: 2.02, 95% confidence interval [CI]: 1.09-3.70) and LBBB (OR: 2.96, 95% CI: 2.01-4.42) were predictors of in-hospital mortality in the entire study population. Further analysis of patients with LBBB showed that CKF (OR: 2.93, 95% CI: 1.40-6.12) was the only predictor of in-hospital mortality. Regardless the presenting symptoms, CHF was the final diagnosis in most cases with LBBB.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319714560223