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Advances in radionuclide imaging of cardiac sarcoidosis
Radionuclide imaging for the diagnosis and monitoring of cardiac involvement in sarcoidosis has advanced significantly in recent years. This article is based on published clinical guidelines, literature review and our collective clinical experience. Gallium-67 scintigraphy is among the diagnostic cr...
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| Published in: | British medical bulletin 2015-09, Vol.115 (1), p.151-163 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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| container_end_page | 163 |
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| container_title | British medical bulletin |
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| creator | Kouranos, V Wells, A U Sharma, R Underwood, S R Wechalekar, K |
| description | Radionuclide imaging for the diagnosis and monitoring of cardiac involvement in sarcoidosis has advanced significantly in recent years.
This article is based on published clinical guidelines, literature review and our collective clinical experience.
Gallium-67 scintigraphy is among the diagnostic criteria for cardiac involvement in systemic sarcoidosis, and it is strongly associated with response to treatment. However, fluorine-18, 2-fluoro-deoxyglucose (FDG) positron emission tomography (PET) is now preferred both for diagnosis and for assessing prognosis.
Most data are from small observational studies that are potentially biased.
Quantitative imaging to assess changes in disease activity in response to treatment may lead to FDG-PET having an important routine role in managing cardiac sarcoidosis.
Larger prospective studies are required, particularly to assess the effectiveness of radionuclide imaging in improving clinical management and outcome. |
| doi_str_mv | 10.1093/bmb/ldv033 |
| format | article |
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This article is based on published clinical guidelines, literature review and our collective clinical experience.
Gallium-67 scintigraphy is among the diagnostic criteria for cardiac involvement in systemic sarcoidosis, and it is strongly associated with response to treatment. However, fluorine-18, 2-fluoro-deoxyglucose (FDG) positron emission tomography (PET) is now preferred both for diagnosis and for assessing prognosis.
Most data are from small observational studies that are potentially biased.
Quantitative imaging to assess changes in disease activity in response to treatment may lead to FDG-PET having an important routine role in managing cardiac sarcoidosis.
Larger prospective studies are required, particularly to assess the effectiveness of radionuclide imaging in improving clinical management and outcome.</description><identifier>EISSN: 1471-8391</identifier><identifier>DOI: 10.1093/bmb/ldv033</identifier><identifier>PMID: 26311504</identifier><language>eng</language><publisher>England</publisher><subject>Cardiomyopathies - diagnostic imaging ; Fluorodeoxyglucose F18 ; Gallium Radioisotopes ; Humans ; Myocardial Perfusion Imaging - methods ; Myocardial Perfusion Imaging - trends ; Positron-Emission Tomography - methods ; Positron-Emission Tomography - trends ; Prognosis ; Sarcoidosis - diagnostic imaging ; Tomography, Emission-Computed, Single-Photon - methods ; Tomography, Emission-Computed, Single-Photon - trends</subject><ispartof>British medical bulletin, 2015-09, Vol.115 (1), p.151-163</ispartof><rights>The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26311504$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kouranos, V</creatorcontrib><creatorcontrib>Wells, A U</creatorcontrib><creatorcontrib>Sharma, R</creatorcontrib><creatorcontrib>Underwood, S R</creatorcontrib><creatorcontrib>Wechalekar, K</creatorcontrib><title>Advances in radionuclide imaging of cardiac sarcoidosis</title><title>British medical bulletin</title><addtitle>Br Med Bull</addtitle><description>Radionuclide imaging for the diagnosis and monitoring of cardiac involvement in sarcoidosis has advanced significantly in recent years.
This article is based on published clinical guidelines, literature review and our collective clinical experience.
Gallium-67 scintigraphy is among the diagnostic criteria for cardiac involvement in systemic sarcoidosis, and it is strongly associated with response to treatment. However, fluorine-18, 2-fluoro-deoxyglucose (FDG) positron emission tomography (PET) is now preferred both for diagnosis and for assessing prognosis.
Most data are from small observational studies that are potentially biased.
Quantitative imaging to assess changes in disease activity in response to treatment may lead to FDG-PET having an important routine role in managing cardiac sarcoidosis.
Larger prospective studies are required, particularly to assess the effectiveness of radionuclide imaging in improving clinical management and outcome.</description><subject>Cardiomyopathies - diagnostic imaging</subject><subject>Fluorodeoxyglucose F18</subject><subject>Gallium Radioisotopes</subject><subject>Humans</subject><subject>Myocardial Perfusion Imaging - methods</subject><subject>Myocardial Perfusion Imaging - trends</subject><subject>Positron-Emission Tomography - methods</subject><subject>Positron-Emission Tomography - trends</subject><subject>Prognosis</subject><subject>Sarcoidosis - diagnostic imaging</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><subject>Tomography, Emission-Computed, Single-Photon - trends</subject><issn>1471-8391</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNo1z81KAzEUhuEgiK2tGy9AsnQzNic_TbIsxT8ouLHr4UySlsjMZEw6Be_eAevq2zx88BJyD-wJmBWrpmtWrT8zIa7IHKSGyggLM3JbyhdjIAQzN2TG1wJAMTkneuPP2LtQaOxpRh9TP7o2-kBjh8fYH2k6UIfZR3S0YHYp-lRiWZLrA7Yl3F12QfYvz5_bt2r38fq-3eyqASScKqfBGu0abjVHQFDgeOBeWS2BM-MxiLWcBFfWMCW9k4pZaz1A4LxBJxbk8e93yOl7DOVUd7G40LbYhzSWGvSUbaRkeqIPFzo2XfD1kKeE_FP_x4pfom5SQw</recordid><startdate>201509</startdate><enddate>201509</enddate><creator>Kouranos, V</creator><creator>Wells, A U</creator><creator>Sharma, R</creator><creator>Underwood, S R</creator><creator>Wechalekar, K</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201509</creationdate><title>Advances in radionuclide imaging of cardiac sarcoidosis</title><author>Kouranos, V ; Wells, A U ; Sharma, R ; Underwood, S R ; Wechalekar, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p141t-c71987cb2972a1a151c2e2d59741208dae3649872598054dc450999d11e22bac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Cardiomyopathies - diagnostic imaging</topic><topic>Fluorodeoxyglucose F18</topic><topic>Gallium Radioisotopes</topic><topic>Humans</topic><topic>Myocardial Perfusion Imaging - methods</topic><topic>Myocardial Perfusion Imaging - trends</topic><topic>Positron-Emission Tomography - methods</topic><topic>Positron-Emission Tomography - trends</topic><topic>Prognosis</topic><topic>Sarcoidosis - diagnostic imaging</topic><topic>Tomography, Emission-Computed, Single-Photon - methods</topic><topic>Tomography, Emission-Computed, Single-Photon - trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kouranos, V</creatorcontrib><creatorcontrib>Wells, A U</creatorcontrib><creatorcontrib>Sharma, R</creatorcontrib><creatorcontrib>Underwood, S R</creatorcontrib><creatorcontrib>Wechalekar, K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British medical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kouranos, V</au><au>Wells, A U</au><au>Sharma, R</au><au>Underwood, S R</au><au>Wechalekar, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Advances in radionuclide imaging of cardiac sarcoidosis</atitle><jtitle>British medical bulletin</jtitle><addtitle>Br Med Bull</addtitle><date>2015-09</date><risdate>2015</risdate><volume>115</volume><issue>1</issue><spage>151</spage><epage>163</epage><pages>151-163</pages><eissn>1471-8391</eissn><abstract>Radionuclide imaging for the diagnosis and monitoring of cardiac involvement in sarcoidosis has advanced significantly in recent years.
This article is based on published clinical guidelines, literature review and our collective clinical experience.
Gallium-67 scintigraphy is among the diagnostic criteria for cardiac involvement in systemic sarcoidosis, and it is strongly associated with response to treatment. However, fluorine-18, 2-fluoro-deoxyglucose (FDG) positron emission tomography (PET) is now preferred both for diagnosis and for assessing prognosis.
Most data are from small observational studies that are potentially biased.
Quantitative imaging to assess changes in disease activity in response to treatment may lead to FDG-PET having an important routine role in managing cardiac sarcoidosis.
Larger prospective studies are required, particularly to assess the effectiveness of radionuclide imaging in improving clinical management and outcome.</abstract><cop>England</cop><pmid>26311504</pmid><doi>10.1093/bmb/ldv033</doi><tpages>13</tpages></addata></record> |
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| identifier | EISSN: 1471-8391 |
| ispartof | British medical bulletin, 2015-09, Vol.115 (1), p.151-163 |
| issn | 1471-8391 |
| language | eng |
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| source | Oxford Journals Online |
| subjects | Cardiomyopathies - diagnostic imaging Fluorodeoxyglucose F18 Gallium Radioisotopes Humans Myocardial Perfusion Imaging - methods Myocardial Perfusion Imaging - trends Positron-Emission Tomography - methods Positron-Emission Tomography - trends Prognosis Sarcoidosis - diagnostic imaging Tomography, Emission-Computed, Single-Photon - methods Tomography, Emission-Computed, Single-Photon - trends |
| title | Advances in radionuclide imaging of cardiac sarcoidosis |
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